Evidence map›Paper›PMID 40099894›Full record

ArticleThe Journal of infectious diseases2025

Recovery of Antibody Immunity After a Resurgence of Respiratory Syncytial Virus Infections.

Frederic Reicherz, Marina Viñeta Paramo, Jeffrey N Bone, Alexanne Lavoie, Sirui Li, Liam Golding, Agatha Jassem, Allison Watts, Bahaa Abu-Raya, Pascal M Lavoie

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Frederic ReicherzBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Marina Viñeta ParamoBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID 0000-0003-1096-3831
Jeffrey N BoneBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID 0000-0001-7704-1677
Alexanne LavoieBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Sirui LiBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID 0009-0009-6361-154X
Liam GoldingBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID 0000-0002-8851-8052
Agatha JassemPublic Health Laboratory, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.ORCID 0000-0002-4128-2919
Allison WattsBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Bahaa Abu-RayaBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Pascal M LavoieBritish Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID 0000-0002-2205-0362

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Longitudinal measurements of respiratory syncytial virus (RSV) immunity over 4 winter seasons reveal that viral neutralization titers, RSV prefusion F protein (pre-F)-specific immunoglobulin M and immunoglobulin G (IgG) levels, and RSV antibody-dependent cellular phagocytosis function gradually returned to prepandemic levels in female healthcare and school workers of childbearing age after 2 winter seasons, following the resurgence of RSV cases in the Vancouver metropolitan region (British Columbia, Canada). In contrast, pre-F IgG avidity profiles remained unchanged. These findings support the notion that repeated viral infections are necessary to maintain high RSV antibody levels in the population.

Indexed as

Antibodies, ViralRespiratory Syncytial VirusesRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAdolescentAdultAntibodies, NeutralizingBritish ColumbiaFemaleHumansImmunoglobulin GImmunoglobulin MLongitudinal StudiesMaleMiddle AgedPhagocytosisAntibodies, NeutralizingAntibodies, ViralImmunoglobulin GImmunoglobulin MantibodyFc functionimmunityneutralizationrespiratory syncytial virus

Identifiers

PMID40099894
PMCPMC12128052

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.