Evidence map›Paper›PMID 40099782›Full record

ReviewOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2025

Charles Bonnet Syndrome associated with unilateral vision loss: A new diagnostic perspective.

Giovanni Forte, Natalie Assaf, Paolo Forte, Jasleen K Jolly

Abstract readCase ReportsReview
In one paragraph

Review in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Charles Bonnet Syndrome associated with unilateral vision loss: A new diagnostic perspective.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giovanni ForteVision and Eye Research Institute, Anglia Ruskin University, Cambridge, UK.ORCID 0009-0006-7642-8080
Natalie AssafVision and Eye Research Institute, Anglia Ruskin University, Cambridge, UK.ORCID 0009-0005-7452-9446
Paolo ForteEye Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID 0000-0003-1762-3506
Jasleen K JollyVision and Eye Research Institute, Anglia Ruskin University, Cambridge, UK.ORCID 0000-0001-9878-4621

Funding

Anglia Ruskin UniversityCollegio Ghislieri di Pavia
6 · The paper itself

Abstract

purposeTo increase recognition of Charles Bonnet Syndrome (CBS) beyond its conventional association with 'significant vision loss', which is indicated in the current literature as a diagnostic criterion.

methodsClinical observation of CBS associated with unilateral visual loss following enucleation due to choroidal melanoma. Comprehensive visual assessments were performed. The cognitive function was assessed with the Montreal Cognitive Assessment (MoCA)-BLIND. The phenomenology, occurrence and impact of visual hallucinations were evaluated using the University of Miami Parkinson's Disease Hallucinations Questionnaire (UM-PDHQ). A critical literature review of CBS cases associated with vision loss in one eye only was conducted.

resultsIn this case and in an additional nine reported cases in the literature, CBS hallucinations occurred following unilateral vision loss despite preserved visual function in the fellow eye. These hallucinations are phenomenologically consistent with those observed after severe bilateral vision loss, indicating that both conditions can lead to the development of CBS.

conclusionsCBS should be screened in all patients who have experienced any degree of vision loss.

Indexed as

BlindnessCharles Bonnet SyndromeHallucinationsVisual AcuityHumansCharles Bonnet Syndromemonocularocular melanomasensory deafferentationvisual hallucinationsvisual release hallucinations

Identifiers

PMID40099782
PMCPMC11976511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.