Evidence map›Paper›PMID 40099756›Full record

ArticleClinical cardiology2025

Long-Term Effects of Left Bundle Branch Area Pacing Versus Traditional Right Ventricular Pacing on Atrial Fibrillation After Dual-Chamber Pacemaker Implantation.

Jieruo Chen, Zefeng Wang, Fei Hang, Weiping Sun, Haiwei Li, Yongquan Wu

Abstract readComparative Study
In one paragraph

Article in Clinical cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Risk factors of atrial fibrillation progression in patients with congenital heart disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jieruo ChenDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0001-7687-4431
Zefeng WangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Fei HangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Weiping SunDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Haiwei LiDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yongquan WuDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0001-9156-4669

Funding

This research received funding from the Clinical Technology Innovation Project of Beijing Hospital Management Center.
6 · The paper itself

Abstract

backgroundTraditional right ventricular pacing (RVP) can lead to asynchronous cardiac mechanical contractions and increase the risk of atrial fibrillation (AF). This study aimed to compare the occurrence of new-onset AF and the progression of AF between novel physiological pacing-left bundle branch area pacing (LBBAP) and RVP with a long-term follow-up. METHODS AND

resultsPatients with a dual-chamber permanent pacemaker initial implantation, no history of persistent AF, and an expected high proportion of ventricular pacing (VP ≥ 20%) were included in this retrospective cohort study (LBBAP, n = 122; RVP, n = 166). The pacing QRS duration (QRSd) of the LBBAP was significantly shorter than that of the RVP (113 ± 22 vs. 140 ± 27 ms, p < 0.001), while the intrinsic QRSd values from the two groups were comparable. During a mean follow-up of 21.9 ± 9.4 months, the composite outcome of postoperative new-onset AF or AF progression was higher in the RVP group than in the LBBAP group (RVP HR 2.62, 95%CI 1.21-5.67, p = 0.014). Left ventricular end-diastolic diameter (LVEDD) levels decreased in the LBBAP group at 1 year follow-up (50 ± 6 vs. baseline 48 ± 6, p = 0.002).

conclusionsIn a mean follow-up period of 2 years, compared to RVP, LBBAP patients with VP ≥ 20% had a decreased risk of occurrence and progression of AF events.

Indexed as

Atrial FibrillationBundle of HisCardiac Pacing, ArtificialHeart RateHeart VentriclesPacemaker, ArtificialVentricular Function, RightAgedDisease ProgressionElectrocardiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective Studiesatrial fibrillationdual‐chamber permanent pacemakerleft bundle branch area pacingpacingphysiological pacing

Identifiers

PMID40099756
PMCPMC11915351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.