Evidence map›Paper›PMID 40099678›Full record

ArticleCornea2025

Processing Methods Affect Biological Properties of Amniotic Membrane Sheet Products.

Yuan Zhang, Allison Helman, Olivia G Mead, Sean Tighe, Yingting Zhu, Scheffer C G Tseng

Abstract read
In one paragraph

Article in Cornea, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. CD44 signaling in skin wound healing and regeneration.Journal of translational medicine · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan ZhangR&D Department, BioTissue Holdings Inc, Miami, FL .
Allison Helman
Sean Tighe
Yingting Zhu
Scheffer C G Tseng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractAmniotic membrane (AM) is widely used in ophthalmology because of its antiinflammatory, antiscarring, and wound healing promoting properties, which are due in part to a key matrix component, heavy chain-hyaluronan/pentraxin3. Herein, we assess various processing methods used to manufacture AM sheet products and their effect on the biological properties of AM mediated by heavy chain-hyaluronan/pentraxin3.

Indexed as

AmnionBiological DressingsC-Reactive ProteinHumansHyaluronic AcidPentraxinsSerum Amyloid P-ComponentWound HealingC-Reactive ProteinHyaluronic AcidPentraxinsSerum Amyloid P-Componentamniotic membraneaseptic processingcryopreservationdehydrationHC-HA/PTX3lyophilizationpotency assayterminal sterilization

Identifiers

PMID40099678
PMCPMC12052046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.