Evidence map›Paper›PMID 40099462›Full record

ArticleActa orthopaedica2025

Time trends in spine surgery in Italy: a nationwide, population-based study of 1,560,969 records of administrative health data from 2001 to 2019.

Marina Torre, Andrea Piazzolla, Enrico Ciminello, Tiziana Falcone, Eugenio Carrani, Simona Pascucci, Michela Franzò, Giuseppe Barbagallo, Vincenzo Vitiello, Gustavo Zanoli and 5 more

Abstract read
In one paragraph

Article in Acta orthopaedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marina TorreItalian National Institute of Health, Rome, Italy. marina.torre@iss.it.ORCID 0000-0003-3851-187X
Andrea PiazzollaUOSD Spinal Deformity Center, AOU Consorziale "Policlinico", Bari, Italy.
Enrico CiminelloItalian National Institute of Health, Rome, Italy.
Tiziana FalconeItalian National Institute of Health, Rome, Italy.
Eugenio CarraniItalian National Institute of Health, Rome, Italy.
Simona PascucciItalian National Institute of Health, Rome; Department of Mechanical and Aerospace Engineering, "Sapienza" University of Rome, Rome, Italy.
Michela FranzòItalian National Institute of Health, Rome; Department of Mechanical and Aerospace Engineering, "Sapienza" University of Rome, Rome, Italy.
Giuseppe BarbagalloDepartment of Neurosurgery, University of Catania, Catania, Italy.
Vincenzo VitielloDepartment of Neurosurgery, San Giovanni Bosco Hospital, Naples, Italy.
Gustavo ZanoliDepartment of Orthopedics, Casa di Cura Santa Maria Maddalena, Occhiobello (RO), Italy.ORCID 0000-0002-6213-9089
Alessia BiondiItalian National Institute of Health, Rome, Italy.
Letizia SampaoloItalian National Institute of Health, Rome, Italy.
Veronica MariItalian National Institute of Health, Rome, Italy.
Francesco LangellaIRCCS Ospedale Galeazzi-Sant’Ambrogio, Milan, ItalyORCID 0000-0002-8639-8480
Pedro BerjanoIRCCS Ospedale Galeazzi-Sant’Ambrogio, Milan, Italy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe use of spinal implants has increased substantially. Their widespread use raises public health concerns. We aimed to study spinal surgery trends in Italy from 2001 to 2019 and present a mapping for ICD9-CM codes potentially related to spinal diagnoses and procedures.

methodsICD9-CM codes of interest were selected and mapped to clinically meaningful spinal diagnostic categories and procedure classes. The Italian National Hospital Discharge Records database was then browsed according to these codes. Surgical volumes and trends were described. Population incidence rates (IR) were estimated and provided with 95% confidence intervals (CI). Variations in IRs were reported in terms of incidence rate ratio. The statistical significance of counts and IR time series trends was assessed by using the Cox-Stuart test.

results1,560,969 spinal procedures were extracted from 209,818,966 admissions registered nationally. The annual number of spinal procedures increased significantly by 67%, from 58,369 in 2001 to 97,636 in 2019 (P < 0.002). 1,040,326 (67%) procedures did not include implants, while 590,643 (33%) used implants, 395,450 (25%) associated with fusions and 125,193 (8%) with non-fusions. Population IRs increased from 100.9 (CI 100.1-101.7) to 163.2 (CI 162.2-164.3) episodes per 100,000 inhabitants. Surgical volumes for non-implant-related procedures remained stable, while implant-related procedures increased significantly, by 420% over the 19 observed years (P = 0.002).

conclusionSpinal surgical procedures and their population incidence rates increased significantly. Fusions and other implant-related procedures increased substantially for most diagnostic categories. An ICD9-CM mapping for spinal diagnoses and procedures as a reproducible tool for further explorations was presented.

Indexed as

Orthopedic ProceduresSpinal DiseasesAdultAgedDatabases, FactualFemaleHumansIncidenceItalyMaleMiddle AgedSpinal Fusion

Identifiers

PMID40099462
PMCPMC11971841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.