ArticleCureus2025
Stress and Gastroesophageal Reflux Disease: Are They Related?
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Development and validation of an early warning model for postoperative reflux in patients with esophageal cancer.Asia-Pacific journal of oncology nursing · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastroesophageal reflux disease (GERD) is a common complaint seen in medical clinics today, affecting countless people worldwide. Patients can present with a wide array of symptoms, ranging from classical complaints like heartburn and acid reflux to atypical cases like silent GERD. Recent advancements in diagnostic testing and imaging have aided in diagnosing and understanding GERD. Given the prevalence of GERD and stress within the confines of our society, it is pertinent to establish a correlation between these two, which this study aimed to investigate.
methodsA cross-sectional study was conducted using the Gastroesophageal Reflux Disease Questionnaire (GERDQ), the Perceived Stress Scale (PSS), and the Student Stress Inventory (SSI), combined in a survey distributed to participants online. These included students from various healthcare institutes.
resultsA total of 439 responses were analyzed, of which 262 (59.7%) were female and 177 (40.3%) were male. Of them, 319 (72.7%) were day scholars, and 120 (27.3%) were students living in hostel accommodation. The mean age was 20.5 years. Female participants had a significantly higher prevalence of GERD (16.4%, n = 43) than male participants (9.6%, n = 17) (p < 0.05). Similar trends were seen in both stress scales, with the female group showing a significantly higher proportion of high-stress individuals (p < 0.05). Program of study, age, accommodation, year of study, hours of sleep, and hours of study had no significant impact on the presence of GERD. However, when the same variables were analyzed against levels of stress, the mean hours of study and mean hours of sleep were significant in the SSI (p < 0.05). The high-stress group in the SSI had a significantly higher mean sleep duration (7.93 hours) and mean study duration (5.77 hours) than both the moderate-stress and low-stress groups.
conclusionResults of this study show that increased stress has a positive correlation with the prevalence of symptoms of GERD. Steps should be taken to reduce stress among medical students to alleviate such symptoms.
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