Evidence map›Paper›PMID 40098918›Full record

ArticleBMJ open sport & exercise medicine2025

Home-based exercise and PHysical activity maintenance interventiOn after livEr traNsplantation: Impact of eXercise intensity (PHOENIX-Liver).

Stefan De Smet, Sofie Leunis, Hanne Van Criekinge, Marieke Vandecruys, Lieze Vrancken, Marie Renier, Steffen Fieuws, Kaatje Goetschalckx, Jeroen Luyten, Jeroen Raes and 5 more

Abstract read
In one paragraph

Article in BMJ open sport & exercise medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Stefan De Smet *Exercise physiology research group, Department of movement sciences, KU Leuven, Leuven, Belgium.ORCID 0000-0001-8739-576X
Sofie Leunis *Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.ORCID 0000-0001-5275-585X
Hanne Van CriekingeDepartment of Microbiology, Immunology and Transplantation, Abdominal Transplantation, KU Leuven, Leuven, Belgium.ORCID 0009-0001-1570-1569
Marieke VandecruysDepartment of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven, Belgium.ORCID 0000-0003-2806-4201
Lieze VranckenKatholieke Universiteit Leuven, Leuven, Belgium.ORCID 0009-0003-6036-3436
Marie RenierDepartment of Rehabilitation Sciences, Research Group for Rehabilitation in Internal Disorders, KU Leuven, Leuven, Flanders, Belgium.ORCID 0009-0003-6544-5940
Steffen FieuwsDepartment public health and primary care, I-BioStat, KU Leuven University Hospitals Leuven Gasthuisberg Campus, Leuven, Flanders, Belgium.
Kaatje GoetschalckxDepartment of Cardiovascular Diseases, UZ Leuven, Leuven, Flanders, Belgium.
Jeroen LuytenDepartment of Public Health and Primary Care, Unit for Health Technology Assessment Research, KU Leuven, Leuven, Flanders, Belgium.ORCID 0000-0001-6398-4025
Jeroen RaesDepartment of Microbiology and Immunology, Katholieke Universiteit Leuven Rega Institute for Medical Research, Leuven, Flanders, Belgium.
Stijn BogaertsDepartment of Development and Regeneration, Locomotor and Neurological Disorders, KU Leuven University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0001-5708-2439
Sabina De GeestNursing Science, Department Public Health, Faculty of Medicine, University of Basel, Basel, BS, Switzerland.ORCID 0000-0001-6596-7237
Amaryllis H Van CraenenbroeckDepartment of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven, Belgium.ORCID 0000-0003-4728-9406
Véronique CornelissenGroup Rehabilitation in Internal Disorders, Katholieke Universiteit Leuven Department of Rehabilitation Sciences, Leuven, Vlaanderen, Belgium.ORCID 0000-0002-0578-4954
Diethard MonbaliuDepartment of Microbiology, Immunology and Transplantation, Abdominal Transplantation, KU Leuven, Leuven, Belgium.ORCID 0000-0002-0506-1609

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplant recipients experience comorbidities, including impaired physical fitness, which could be managed by exercise and physical activity interventions. This study aims to evaluate the feasibility, clinical effectiveness and cost-effectiveness of a 6-month exercise intervention, followed by a 15-month tailored physical activity maintenance intervention, in de novo liver transplant recipients. This single-centre, randomised, controlled, single-blinded trial will recruit 147 adult liver transplant recipients at 3-5 months post-transplant. Participants will be randomised into (1) 6 months of enhanced usual care, not followed by a physical activity intervention (control (CON) group, n=49), (2) 6 months of moderate-intensity exercise training, followed by a physical activity intervention (moderate-intensity training (MIT) group; n=49) or (3) consecutively 3 months of moderate-intensity exercise training, 3 months of high-intensity interval training and a physical activity intervention (moderate and high-intensity training (MHIT) group; n=49). Exercise training will consist of home-based stationary bicycling and muscle-strengthening exercises, partially supervised by participants' local physiotherapists. The physical activity intervention includes an array of behaviour change techniques. Primary hypothesis: after the exercise intervention, peak oxygen uptake (V̇O

Indexed as

ExerciseLiverPhysical activityPhysical fitness

Identifiers

PMID40098918
PMCPMC11911812

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.