Evidence map›Paper›PMID 40098863›Full record

ArticleAnnals of thoracic surgery short reports2025

Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.

Berk Aykut, Douglas M Overbey, Cathlyn K Medina, Tariq M Omer, T Konrad Rajab, Smith M Ngeve, Ziv Beckerman, Joseph W Turek

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Berk AykutDuke Congenital Heart Surgery Research and Training Laboratory, Durham, North Carolina.
Douglas M OverbeyDuke Congenital Heart Surgery Research and Training Laboratory, Durham, North Carolina.
Cathlyn K MedinaDuke Congenital Heart Surgery Research and Training Laboratory, Durham, North Carolina.
Tariq M OmerDuke Congenital Heart Surgery Research and Training Laboratory, Durham, North Carolina.
T Konrad RajabArkansas Children's Hospital, Little Rock, Arkansas.
Smith M NgeveDuke Congenital Heart Surgery Research and Training Laboratory, Durham, North Carolina.
Ziv BeckermanDuke Congenital Heart Surgery Research and Training Laboratory, Durham, North Carolina.
Joseph W TurekDuke Congenital Heart Surgery Research and Training Laboratory, Durham, North Carolina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Partial heart transplantation (PHT) has emerged as a pioneering approach for treating infants with irreparable heart valve dysfunction. However, the scarcity of suitable donors presents a significant bottleneck to its widespread application. This study introduces and evaluates the novel use of domino and split-root procedures within PHT. Methods: We describe 6 pediatric cardiac patients who underwent either domino or split-root PHT at our institution. Results: From May to August 2023, our team successfully executed 3 domino and 3 split-root PHTs, including 1 procedure that involved interinstitutional collaboration. These cases highlight the procedural feasibility and the potential for broader application. Conclusions: The implementation of PHT represents a significant advance in pediatric heart care. Domino and split-root techniques within the PHT framework have the potential to substantially increase both donor availability and recipient capacity. These strategies usher in a new era of organ stewardship through addressing the challenge of donor organ shortage.

Identifiers

PMID40098863
PMCPMC11910830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.