Evidence map›Paper›PMID 40098838›Full record

ArticleAnnals of thoracic surgery short reports2025

Association of Pre-Lung Transplant Opioid Use With Posttransplant Opioid Use and Outcomes.

Jessica M Ruck, Camille Hage, Tao Liang, Darren E Stewart, Jinny S Ha, Allan B Massie, Dorry L Segev, Christian A Merlo, Errol L Bush

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Psychosocial challenges with transplantation.Current opinion in pulmonary medicine · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jessica M RuckDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.
Camille HageDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.
Tao LiangDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.
Darren E StewartDepartment of Surgery, NYU Grossman School of Medicine and Langone Health, New York, New York.
Jinny S HaDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.
Allan B MassieDepartment of Surgery, NYU Grossman School of Medicine and Langone Health, New York, New York.
Dorry L SegevDepartment of Surgery, NYU Grossman School of Medicine and Langone Health, New York, New York.
Christian A MerloDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Errol L BushDepartment of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.

Funding

Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Frailty and post-liver transplant delirium and cognitive impairment in older recipientsF32AG067642 · NIA · JOHNS HOPKINS UNIVERSITY · PI RUCK, JESSICA MOORE · 2021 to 2023
$258k
NIA NIH HHS F32 AG067642NIDDK NIH HHS K24 DK101828
6 · The paper itself

Abstract

Background: Preoperative opioid use (OU) is a strong risk factor for poor postoperative outcomes in other surgical populations but has not been explored in lung transplant (LT) recipients nationally. Methods: The study identified adult (aged ≥18 years) US lung transplant (LT) recipients from 2011 to 2021 in the Scientific Registry of Transplant Recipients with prescription data through a pharmacy data set. Posttransplantation ventilatory support, infection, and mortality by pretransplantation OU (prescription fill ≤6 months before transplantation) were compared using multivariable regression. Results: Among 17,285 LT recipients, 17.9% had pretransplantation OU. The odds of posttransplantation opioid prescription fill were 3.18-fold higher 0 to 6 months after transplantation (adjusted odds ratio [aOR], 3.18; 95% CI, 2.91-3.47; Conclusions: Pretransplantation OU was the strongest independent risk factor for posttransplantation OU and was associated with greater morbidity and mortality. Reducing pretransplantation and posttransplantation OU could benefit LT recipients and should be explored.

Identifiers

PMID40098838
PMCPMC11910811

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.