ArticleFrontiers in oral health2025
Wound healing and pain evaluation following diode laser surgery vs. conventional scalpel surgery in the surgical treatment of oral leukoplakia: a randomized controlled trial.
Article in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Article
- Plant Exosome Injection with or without Low Level Laser Therapy Promotes Skin Wound Healing: An Experimental Study.Plastic and reconstructive surgery. Global open · 2026Article
- Article
- The multistep progression of areca nut-induced oral cancer: a mechanistic roadmap from pathogenesis to precision therapy.Life medicine · 2026Review
- Plant Exosome Injections in Tongue Wounds: A Comparative Histological and Immunohistochemical Experimental Study.Plastic and reconstructive surgery. Global open · 2026Article
- Plant Exosome Injection: A New Boost for Postlaser Vascular Repair.The Journal of clinical and aesthetic dermatology · 2026Article
- Digitally guided diode-laser cheiloplasty for correction of upper-lip asymmetry: a case report.Frontiers in oral health · 2026Article
- High-Energy Lasers in Oral Oncology: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aimed to compare patient-reported pain scores and clinician-assessed healing outcomes following the treatment of oral leukoplakia (OL) with a diode laser vs. a conventional scalpel. Methods: A randomized, double-blind clinical trial (Brazilian Clinical Trials Registry (RBR-7pgcyq) was conducted involving histopathologically confirmed OL patients. Participants were randomly allocated to undergo treatment with either a diode laser or a scalpel. Pain was assessed at 24 h, 48 h, and 7 days using the Visual Analog Scale (VAS), while healing outcomes were clinically evaluated at 7 days, 1-month, and 3-months post-treatment using the Vancouver Scar Scale. Statistical analyses included the Mann-Whitney Results: 64 patients were analyzed (33 in diode laser and 31 in scalpel group). No significant differences in pain scores were observed between the treatment groups at 24 h ( Conclusions: There was no significant difference between the diode laser and scalpel treatment arms regarding post operative pain scores. Diode lasers represent better healing at the first week post treatment, but with no differences over time. These findings support the use of either modality as viable management options for OL. Clinical Trial Registration: Brazilian Clinical Trials Registry, identifier (RBR-7pgcyq).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.