Evidence map›Paper›PMID 40098664›Full record

ArticleInnovation (Cambridge (Mass.))2025

Multi-level genomic convergence of secondary aquatic adaptation in marine mammals.

Shixia Xu, Lei Shan, Ran Tian, Zhenpeng Yu, Di Sun, Zhenhua Zhang, Inge Seim, Ming Zhou, Linxia Sun, Na Liang and 10 more

Abstract read
In one paragraph

Article in Innovation (Cambridge (Mass.)), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. A Near-Telomere-to-Telomere Genome Assembly of the Spotted Seal (International journal of molecular sciences · 2026
    Article
  4. Molecular divergence ofZoological research · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Shixia XuJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Lei ShanJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Ran TianJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Zhenpeng YuJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Di SunJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Zhenhua ZhangJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Inge SeimIntegrative Biology Laboratory, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Ming ZhouJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Linxia SunJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Na LiangJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Qian ZhangJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Simin ChaiSouthern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China.
Daiqing YinSouthern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China.
Luoying DemeJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Tianzhen WuJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Yongjie ChenJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Zhikang XuJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Yu ZhengJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Wenhua RenJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Guang YangJiangsu Key Laboratory for the Biodiversity Conservation and Sustainable Utilization in the Middle and Lower Reaches of Yangtze River Basin, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine mammals provide a valuable model for studying the molecular basis of convergent evolution during secondary aquatic adaptation. Using multi-omics data and functional experiments, including CRISPR-Cas9 mouse models and luciferase reporter assays, this study explored the molecular mechanisms driving this transition across coding regions, regulatory elements, and genomic architecture. Convergent amino acid substitutions in

Indexed as

blubberconvergent evolutionlimb degenerationmarine mammalssecondary aquatic adaptation

Identifiers

PMID40098664
PMCPMC11910941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.