Evidence map›Paper›PMID 40098616›Full record

ArticleFrontiers in pharmacology2025

Quercitrin, the primary active ingredient of

Dan Wu, Bo Xie, Jing Li, Zhangang Xiao, Jing Shen, Xu Wu, Mingxing Li, Qin Sun, Hongping Shen, Xiaobing Li and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dan Wu *Integrated Chinese and Western Medicine School, Southwest Medical University, Luzhou, China.
Bo Xie *Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Jing LiIntegrated Chinese and Western Medicine School, Southwest Medical University, Luzhou, China.
Zhangang XiaoLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Jing ShenLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Xu WuLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Mingxing LiLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Qin SunIntegrated Chinese and Western Medicine School, Southwest Medical University, Luzhou, China.
Hongping ShenIntegrated Chinese and Western Medicine School, Southwest Medical University, Luzhou, China.
Xiaobing LiLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Yong DaiSichuan Police College, Luzhou, Sichuan, China.
Yueshui ZhaoIntegrated Chinese and Western Medicine School, Southwest Medical University, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Methamphetamine (METH), a synthetic psychostimulant and highly addictive drug, could cause depression and acute liver injury. There have been few studies on the mechanism by which METH induces liver damage and on how to alleviate METH-induced hepatic toxicities. Methods: Firstly, we used the MTT assay to screen the active components of AF. Then, UPLC-MS/MS was employed to analyze the effective components and identify their activities. In addition, Results: We found that the ethyl acetate fraction of Conclusion:

Indexed as

apoptosishepatotoxicityoxidative damagequercitrinROS

Identifiers

PMID40098616
PMCPMC11911681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.