Evidence map›Paper›PMID 40098496›Full record

ArticlePsychological science2025

*Co-Occurrence and Causality Among ADHD, Dyslexia, and Dyscalculia.

Elsje van Bergen, Eveline L de Zeeuw, Sara A Hart, Dorret I Boomsma, Eco J C de Geus, Kees-Jan Kan

Abstract readTwin Study
In one paragraph

Article in Psychological science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Reading Disabilities With and Without Co-Occurring ADHD: No Evidence for Additive Impact on Reading Skills.Scientific studies of reading : the official journal of the Society for the Scientific Study of Reading · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elsje van BergenDepartment of Biological Psychology, Vrije Universiteit (VU) Amsterdam.ORCID 0000-0002-5860-5745
Eveline L de ZeeuwDepartment of Biological Psychology, Vrije Universiteit (VU) Amsterdam.ORCID 0000-0001-9042-7419
Sara A HartDepartment of Psychology, University of Waterloo.
Dorret I BoomsmaDepartment of Biological Psychology, Vrije Universiteit (VU) Amsterdam.ORCID 0000-0002-7099-7972
Eco J C de GeusDepartment of Biological Psychology, Vrije Universiteit (VU) Amsterdam.
Kees-Jan KanResearch Institute of Child Development and Education, University of Amsterdam.

Funding

EPA EP-C-15-001Non-US Government Research Support type
6 · The paper itself

Abstract

ADHD, dyslexia, and dyscalculia often co-occur, and the underlying continuous traits are correlated (ADHD symptoms, reading, spelling, and math skills). This may be explained by trait-to-trait causal effects, shared genetic and environmental factors, or both. We studied a sample of ≤ 19,125 twin children and 2,150 siblings from the Netherlands Twin Register, assessed at ages 7 and 10. Children with a condition, compared to those without that condition, were 2.1 to 3.1 times more likely to have a second condition. Still, most children (77.3%) with ADHD, dyslexia, or dyscalculia had just one condition. Cross-lagged modeling suggested that reading causally influences spelling (β = 0.44). For all other trait combinations, cross-lagged modeling suggested that the trait correlations are attributable to genetic influences common to all traits, rather than causal influences. Thus, ADHD, dyslexia, and dyscalculia seem to co-occur because of correlated genetic risks, rather than causality.

Indexed as

Attention Deficit Disorder with HyperactivityDiseases in TwinsDyscalculiaDyslexiaChildComorbidityFemaleGenetic Predisposition to DiseaseHumansMaleNetherlandsRegistriesSiblingsbehavioural difficultiescomorbidityenvironmental influencesheritabilityindividual differenceslearning difficultiesopen materials

Identifiers

PMID40098496
PMCPMC13428880

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.