Evidence map›Paper›PMID 40098345›Full record

ArticleClinical psychology & psychotherapy

The Interplay Between Personality and Clinical Syndromes in Eating Disorders: Implications for Personalized Treatment.

Paolo Meneguzzo, Francesca Buscaglia, Anna Pillan, Enrica Bucci, Alice Garolla, Anna Marzotto, Chiara Cazzola, Roberta Castegnaro, Elisa Bonello, Patrizia Todisco

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Article in Clinical psychology & psychotherapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paolo MeneguzzoDepartment of Neuroscience, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0003-3323-6071
Francesca BuscagliaEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Anna PillanEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Enrica BucciEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Alice GarollaEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Anna MarzottoEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Chiara CazzolaEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Roberta CastegnaroEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Elisa BonelloEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.
Patrizia TodiscoEating Disorder Unit, Casa di Cura "Villa Margherita" - KOS Group, Arcugnano, Vicenza, Italy.ORCID https://orcid.org/0000-0002-2212-9855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEating disorders (EDs) are complex and multifactorial conditions with significant impacts on both physical and mental health. Despite advances in treatment, relapse rates remain high, highlighting the need for improved predictive models for treatment outcomes. This study aims to examine the role of personality traits and clinical syndromes, as assessed by the Millon Clinical Multiaxial Inventory-III (MCMI-III), in predicting treatment outcomes for individuals with EDs.

methodsA retrospective evaluation was conducted on 149 women diagnosed with EDs, receiving inpatient treatment at the Eating Disorder Unit of Casa di Cura Villa Margherita-KOS (Arcugnano-Vicenza) between 2020 and 2024. Participants completed the MCMI-III at treatment initiation, with the Eating Disorder Examination Questionnaire (EDE-Q) and Clinical Impairment Assessment (CIA) administered at baseline and discharge.

resultsRegression analyses revealed that maladaptive personality traits (avoidant, dependent and histrionic) and clinical syndromes such as major depression were significant negative predictors of treatment response. In contrast, post-traumatic stress emerged as a positive predictor of improvement. Specific personality and clinical patterns were associated with changes in symptomatology, including reductions in eating concerns, shape concerns and clinical impairment. However, not all dimensions were predictive of treatment outcomes.

conclusionThis study underscores the importance of personalized treatment approaches that account for both personality traits and clinical syndromes in individuals with EDs. Future research should explore how these factors interact over time and inform tailored therapeutic strategies, particularly for those with comorbid traits or disorders.

Indexed as

Feeding and Eating DisordersPersonalityPersonality DisordersPrecision MedicineAdultFemaleHumansMiddle AgedPersonality InventoryRetrospective StudiesSyndromeTreatment OutcomeYoung Adultclinical impairmentcomorbid traitseating disordersoutcomepersonality traitstreatment response

Identifiers

PMID40098345
PMCPMC11914863

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.