Evidence map›Paper›PMID 40098297›Full record

ArticleJournal of applied clinical medical physics2025

Geometric and dosimetric evaluation of a commercial AI auto-contouring tool on multiple anatomical sites in CT scans.

Robert N Finnegan, Alexandra Quinn, Patrick Horsley, Joseph Chan, Maegan Stewart, Regina Bromley, Jeremy Booth

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robert N FinneganNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Alexandra QuinnNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Patrick HorsleyNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Joseph ChanNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Maegan StewartNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Regina BromleyNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Jeremy BoothNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current radiotherapy practices rely on manual contouring of CT scans, which is time-consuming, prone to variability, and requires highly trained experts. There is a need for more efficient and consistent contouring methods. This study evaluated the performance of the Varian Ethos AI auto-contouring tool to assess its potential integration into clinical workflows. This retrospective study included 223 patients with treatment sites in the pelvis, abdomen, thorax, and head and neck regions. The Ethos AI tool generated auto-contours on each patients' pre-treatment planning CT, and 45 unique structures were included across the study cohort. Multiple measures of geometric similarity were computed, including surface Dice Similarity Coefficient (sDSC) and mean distance to agreement (MDA). Dosimetric concordance was evaluated by comparing mean dose and maximum 2 cm

Indexed as

Head and Neck NeoplasmsImage Processing, Computer-AssistedNeoplasmsRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedAlgorithmsHumansOrgans at RiskRadiometryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRetrospective Studiesartificial intelligenceautomatic contouringdeep learningradiotherapy

Identifiers

PMID40098297
PMCPMC12148769

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.