Evidence map›Paper›PMID 40098197›Full record

ArticleJournal of cardiothoracic surgery2025

Clinical management after surgical left atrial appendage exclusion.

Prashant D Bhave, Karanpreet K Dhaliwal, Sneha Chebrolu, Jonathan Brock, Matthew J Singleton, Karl M Richardson

Abstract read
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In one paragraph

Article in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prashant D BhaveDepartment of Internal Medicine, Section on Cardiovascular Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC, USA. pdbhave@gmail.com.
Karanpreet K DhaliwalDept of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA.
Sneha ChebroluDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Jonathan BrockDepartment of Internal Medicine, Section on Cardiovascular Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC, USA.
Matthew J SingletonWellspan Health, York, PA, USA.
Karl M RichardsonDepartment of Internal Medicine, Section on Cardiovascular Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical left atrial appendage (LAA) closure is an increasingly utilized approach to mitigate the risk of cardioembolic stroke in patients with atrial fibrillation (AF). Consensus is lacking regarding optimal stroke prevention management after surgical LAA management.

objectiveTo elucidate real world clinical management of anticoagulation in patients undergoing surgical LAA management.

methodsOver a 7-year period at a single center, 458 participants carried a diagnosis of AF and underwent surgical exclusion of their LAA during concomitant cardiac surgery. Follow-up was catalogued via retrospective chart review; median follow-up was 2 years. Successful LAA ligation was defined as maximal stump depth < 1.0 cm by transesophageal echocardiography (TEE) without distal leak.

resultsAmong 458 patients, 299 were discharged on OAC (142 DOAC and 157 warfarin). Of these, 31% (94/299) had a follow-up TEE. Among those without a TEE, 32% (65/205) were taken off OAC; among those who underwent TEE, 59% (55/94) were taken off OAC. Using a logistic regression model, there was no relationship between age, sex, CHA

conclusionClinical management after surgical LAA management, particularly with regard to LAA imaging and OAC continuation, is highly heterogeneous.

Indexed as

AnticoagulantsAtrial AppendageAtrial FibrillationCardiac Surgical ProceduresStrokeAgedAged, 80 and overEchocardiography, TransesophagealFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesAnticoagulantsAtrial fibrillationLeft atrial appendageStroke preventionTEE

Identifiers

PMID40098197
PMCPMC11916981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.