Evidence map›Paper›PMID 40098190›Full record

ArticleJournal of medical case reports2025

Mixed sex cord stromal tumor of the testis composed of granulosa, Leydig, and Sertoli cell tumor components: a case report.

Nao Wakimura, Mayumi Akaki Nagayasu, Hiroyuki Tanaka, Takaya Murashima, Masato Fujii, Takahiro Nagai, Shoichiro Mukai, Toshiyuki Kamoto

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nao WakimuraSection of Urology, Koga General Hospital, Miyazaki, Japan.
Mayumi Akaki NagayasuDepartment of Pathology, National Hospital Organization, Miyakonojo Medical Center, Miyazaki, Japan.
Hiroyuki TanakaSection of Pathology, Koga General Hospital, Miyazaki, Japan.
Takaya MurashimaDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Masato FujiiDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Takahiro NagaiDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Shoichiro MukaiDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan. syoichiro_mukai@med.miyazaki-u.ac.jp.ORCID http://orcid.org/0000-0002-1678-8619
Toshiyuki KamotoDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMixed sex cord stromal tumor is defined as a tumor consisting of various combinations of sex cord stromal elements, and the tumor is extremely rare. CASE PRESENTATION: A 76-year-old Japanese male visited our hospital complaining of left scrotal swelling. Magnetic resonance imaging of the mass showed a multilocular cystic pattern with different degrees of intensities in each cyst. The solid component was observed in part showing hypointensity on the T2-weighted image. Although there was no apparent evidence of malignancy in cytology of punctured fluid of the cystic tumor, malignant potential was not ruled out completely. Therefore, transinguinal radical orchiectomy was performed, and the tumor was diagnosed as mixed sex cord stromal tumor consisting of adult-type granulosa cell tumor, Leydig cell tumor and Sertoli cell tumor components. The patient recovered without any postoperative event. In addition, neither apparent recurrence nor metastasis was observed at 7 years after surgery.

conclusionThe tumor showed a multilocular cystic appearance with solid component, which was similar in appearance to previous reports of the same pathological features. Pathological findings of each component were compatible with those of mixed sex cord stromal tumor, and immunohistochemical analysis was useful for accurate diagnosis. The tumor was successfully resected, and no apparent recurrence was observed at 7 years after surgery.

Indexed as

Granulosa Cell TumorLeydig Cell TumorSertoli Cell TumorSex Cord-Gonadal Stromal TumorsTesticular NeoplasmsAgedHumansMagnetic Resonance ImagingMaleOrchiectomyAdult-type granulosa cell tumorLeydig cell tumorMixed sex cord stromal tumorSertoli cell tumorTestis

Identifiers

PMID40098190
PMCPMC11917124

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