Evidence map›Paper›PMID 40098134›Full record

ReviewJournal of medical case reports2025

Oral ulcers in hematological malignancy patients undergoing chemotherapy: is it chemotherapy or neutropenia?: a case report and review of the literature.

Fatima AlZahraa Al Beesh, Nafiza Martini, Siham Suleiman, Abeer Aljoujou

Abstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Symptom burden in patients with hematologic malignancies and its influencing factors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fatima AlZahraa Al BeeshDepartment of Oral Medicine, Faculty of Dentistry, University of Damascus, Damascus, Syrian Arab Republic. albeeshfatima@gmail.com.ORCID http://orcid.org/0009-0008-9948-8689
Nafiza MartiniFaculty of Medicine, University of Damascus, Damascus, Syrian Arab Republic.ORCID http://orcid.org/0000-0002-9289-0674
Siham SuleimanDepartment of Hematology-Oncology, Faculty of Medicine, University of Damascus, Damascus, Syrian Arab Republic.
Abeer AljoujouDepartment of Oral Medicine, Faculty of Dentistry, University of Damascus, Damascus, Syrian Arab Republic.ORCID http://orcid.org/0000-0001-8606-3122

Funding

Damascus University 501100020595
6 · The paper itself

Abstract

backgroundChemotherapy can cause oral complications either directly, by inducing mucosal degeneration, or indirectly, through myelosuppression leading to neutropenia. Neutropenia, a common side effect, is often associated with multiple oral ulcers. CASE PRESENTATION: A 39-year-old Arabic Syrian man with acute myelogenous leukemia developed neutropenia following his initial chemotherapy course, resulting in oral ulcers. A complete blood count confirmed chemotherapy-induced neutropenia, and the clinical presentation supported the diagnosis of neutropenic ulcers. The patient's chemotherapy regimen was temporarily halted, and a topical corticosteroid paste containing triamcinolone acetonide was applied three times daily for 7 days. This treatment led to significant regression of the ulcers. The patient provided written informed consent after receiving a detailed explanation of the study's objectives, procedures, and privacy considerations.

conclusionTopical corticosteroid treatment effectively promoted significant regression of neutropenic ulcers in this case.

Indexed as

Antineoplastic AgentsLeukemia, Myeloid, AcuteNeutropeniaOral UlcerAdultHumansMaleTreatment OutcomeAntineoplastic AgentsChemotherapy-induced neutropeniaNeutropeniaNeutropenic ulcerOral ulcer

Identifiers

PMID40098134
PMCPMC11916965

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Registered trials

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