Evidence map›Paper›PMID 40098042›Full record

ReviewJournal of occupational medicine and toxicology (London, England)2025

A review of silicosis and other silica-related diseases in the engineered stone countertop processing industry.

Jane C Fazio, Karoly Viragh, Jenny Houlroyd, Sheiphali A Gandhi

Abstract readReview
In one paragraph

Review in Journal of occupational medicine and toxicology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Silicosis from dry-cutting engineered stone in the fabrication of countertops.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  2. Artificial stone and silicosis: the Korean experience.Journal of occupational medicine and toxicology (London, England) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jane C FazioDivision of Pulmonary, Critical Care & Sleep Medicine, David Geffen School of Medicine, University of California los Angeles, 43-229 CHS Box 951690, 10833 Le Conte Avenue, Los Angeles, CA, 90095, USA. jfazio@mednet.ucla.edu.
Karoly ViraghDepartment of Radiology, Olive View-UCLA Medical Center, Sylmar, CA, USA.
Jenny HoulroydSafety, Health, and Environmental Services, Enterprise Innovation Institute, Georgia Institute of Technology, Atlanta, GA, USA.
Sheiphali A GandhiDivision of Occupational, Environmental and Climate Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.

Funding

Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
NCATS NIH HHS KL2 TR001870
6 · The paper itself

Abstract

backgroundEngineered stone (ES), a material that has become widespread for its use in kitchen and bathroom countertops since the 1980s, is composed of over 90% crystalline silica by weight, significantly exceeding the silica content of natural stones such as granite (40-50%) and marble (< 10%). Workers fabricating ES are exposed to dangerously high levels of respirable crystalline silica (RCS) and other toxic chemicals, which increases the risk of developing silicosis and other lung and systemic diseases. The purpose of this review is to explore the epidemiology, occupational risks, regulatory gaps, diagnostic evaluation, and clinical challenges associated with ES dust exposure. MAIN BODY: ES silicosis was first described in the early 2010s among ES countertop workers in Spain, Italy, and Israel. Since then, hundreds of cases have emerged worldwide, namely in China, Australia, the United States, the United Kingdom, and Belgium. Silicosis from ES dust is accelerated and diagnosed after 7-19 years of exposure, often affecting young individuals (median age 33-55 years) from marginalized or immigrant communities. Morbidity and mortality are poor, with high rates of lung transplantation and death. Industrial hygiene air sample monitoring data shows that despite engineering controls such as wet saws and exhaust ventilation, exposure to respirable crystalline silica when cutting ES frequently exceeds safe exposure levels. Diagnostic evaluation and treatment are clinically challenging due to delayed medical screening, misdiagnosis, and lack of treatment options.

conclusionsThis review underscores the urgent need for enhanced occupational safety regulations, active screening, and healthcare support to address the rising burden of ES silicosis among vulnerable worker populations globally.

Identifiers

PMID40098042
PMCPMC11917111

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.