ArticleBMC endocrine disorders2025
Smoking is associated with adverse clinical outcomes after thyroidectomy: a 5-year retrospective analysis.
Article in BMC endocrine disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- SHAP-Based Identification of Potential Acoustic Biomarkers in Patients with Post-Thyroidectomy Voice Disorder.Diagnostics (Basel, Switzerland) · 2025Article
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9 authors.
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Abstract
objectiveTobacco use has been confirmed to be a risk factor for postoperative complications, but the impact of smoking on adverse outcomes following thyroidectomy remains largely unknown.
methodsUsing data spanning 2016-2020 from the National Inpatient Sample, patients aged ≥ 18 years who underwent thyroidectomy for thyroid malignancy or other thyroid disorders were identified and classified into two groups: current smokers and non-smokers. We compared outcome variables between the two groups via univariate analysis and adjusted multivariate logistic regression.
resultsThe present study included 13,737 records of patients who underwent thyroidectomy, among whom 1,360 (9.90%) were identified as current smokers. After propensity score matching, logistic regression analysis suggested that smoking was associated with a heightened risk of unfavorable discharge (aOR = 1.27, 95% CI [1.05-1.54], P = 0.012), vocal dysfunction (aOR = 1.25, 95% CI [1.00-1.55], P = 0.049), hypocalcemia (aOR = 1.23, 95% CI [1.05-1.44], P = 0.010), hypomagnesemia (aOR = 1.58, 95% CI [1.19-2.09], P = 0.001), and respiratory complications (aOR = 1.39, 95% CI [1.16-1.68], P < 0.001). Similar results were observed in both patients who underwent thyroidectomy for thyroid malignancy and those who underwent thyroidectomy for other thyroid disorders when a stratified analysis by surgical indications was performed.
conclusionSmoking is an independent risk factor for adverse clinical outcomes after thyroidectomy.
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