Evidence map›Paper›PMID 40097979›Full record

ReviewJournal of translational medicine2025

New insights on anti-tumor immunity of CD8

Yibin Lin, Yifu Song, Yaochuan Zhang, Xiaodong Li, Liang Kan, Sheng Han

Abstract readReview
In one paragraph

Review in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Review
  2. Leveraging Microphysiological Systems to Facilitate Neutrophil-Based Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. C-reactive protein-albumin-lymphocyte index predicts biochemical recurrence in prostate cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. CD8Cancer science · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Diagnostics (Basel, Switzerland) · 2026
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yibin LinDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, 110001, China.
Yifu SongDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, 110001, China.
Yaochuan ZhangDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, 110001, China.
Xiaodong LiDepartment of Neurosurgery, Siping Central People's Hospital, Siping, Jilin, 136000, China.
Liang KanDepartment of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, 110004, China. kanliang31cmu@163.com.
Sheng HanDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, 110001, China. hansheng2001_x@aliyun.com.ORCID 0000-0001-6991-0529

Funding

National Natural Science Foundation of China nos. 82273482 and 81772653
6 · The paper itself

Abstract

Recent breakthroughs in tumor immunotherapy have confirmed the capacity of the immune system to fight several cancers. The effective means of treating cancer involves accelerating the death of tumor cells and improving patient immunity. Dynamic changes in the tumor immune microenvironment alter the actual effects of anti-tumor drug production and may trigger favorable or unfavorable immune responses by modulating tumor-infiltrating lymphocytes. Notably, CD8

Indexed as

CD8-Positive T-LymphocytesImmunotherapyNeoplasmsNeoplastic Stem CellsTumor MicroenvironmentAnimalsHumansCancer prognosisCancer stem cell (CSC)Cytotoxic CD8+ T lymphocyte (CTL)ImmunotherapyTumor immune microenvironment (TIME)

Identifiers

PMID40097979
PMCPMC11912710

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.