Evidence map›Paper›PMID 40097975›Full record

SynthesisBMC public health2025

COVID-19 vaccine acceptance and hesitancy in Cameroon: a systematic review and meta-analysis.

Fabrice Zobel Lekeumo Cheuyem, Adidja Amani, Iyawa Clarisse Alma Nkodo, Lionel Bethold Keubou Boukeng, Michel Franck Edzamba, Ariane Nouko, Edwige Omona Guissana, Christelle Sandrine Ngos, Chabeja Achangwa, Christian Mouangue

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fabrice Zobel Lekeumo CheuyemDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon. zobelcheuyem@gmail.com.
Adidja AmaniDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Iyawa Clarisse Alma NkodoMinistry of Public Health, Yaounde, Cameroon.
Lionel Bethold Keubou BoukengDepartment of Public Health and Social Sciences, Faculty of Medicine and Pharmaceutical Sciences, University of Ebolowa, Ebolowa, Cameroon.
Michel Franck EdzambaDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Ariane NoukoDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Edwige Omona GuissanaMinistry of Public Health, Yaounde, Cameroon.
Christelle Sandrine NgosDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Chabeja AchangwaQueens Elisabeth Commonwealth Scholar (QECS Scholar), University of the West Indies, Cave Hill, Barbados.
Christian MouangueMinistry of Public Health, Yaounde, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development of effective vaccines was a promising tool for ending the pandemic. However, the success of a vaccination programme hinges on achieving substantial community acceptance. In Cameroon, numerous studies have investigated the level of acceptance, hesitancy, and perception of COVID-19 vaccines, with mixed results. To provide a comprehensive understanding of these parameters, this meta-analysis aimed to estimate the pooled proportion of COVID-19 vaccine acceptance, hesitancy and perception in Cameroon.

methodsA systematic search of online databases, including PubMed, Google Scholar, and ScienceDirect, was conducted to identify relevant research articles. This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The extracted data were compiled in a Microsoft Excel spreadsheet and analyzed using R statistical software (version 4.3.3). The pooled proportion of COVID-19 vaccine acceptance, hesitancy, and perception was calculated using a random-effects meta-analysis. Funnel plots, Egger's, and Begg's tests were used to assess publication bias.

resultsOf the 1,346 records identified through the database search, 20 research articles were included in the systematic review and meta-analysis. The random-effects model showed that approximately 31.21% (95% CI: 23.49-38.94) of the participants was willing to accept the COVID-19 vaccine. More than two-thirds of the population (68.49%; 95% CI: 60.65-76.34) were vaccine hesitant. Half of the participants (51.81%; 95% CI: 42.70-60.93), had a negative perception of the COVID-19 vaccine. The acceptance rate progressed from the first semester of 2021 (27.21%; 95% CI: 10.38-44.05) to the first semester of 2022 (45.56%; 95% CI: 25.00-66.12). The pooled vaccine acceptance rate was 29.29% (95% CI: 19.86-38.72) for the general population and 39.24% (95% CI: 22.84-55.64) for healthcare workers. The pooled vaccine hesitancy rate was 70.39% (95% CI: 61.30-79.80) for the general population and 57.42% (95% CI: 4.05-71.80) for healthcare workers.

conclusionAlthough progress in vaccine acceptance, targeted interventions remain necessary to address vaccine hesitancy in the country. Strategies such as enhancing access to accurate information, fostering trust in institutions, and strengthening community engagement remain crucial for increasing COVID-19 vaccine uptake.

Indexed as

COVID-19COVID-19 VaccinesPatient Acceptance of Health CareVaccination HesitancyCameroonHumansCOVID-19 VaccinesAcceptanceCameroonCOVID-19 vaccineHesitancyPerception

Identifiers

PMID40097975
PMCPMC11916848

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.