Evidence map›Paper›PMID 40097940›Full record

ArticleBMC gastroenterology2025

Using a nomogram based on the controlling nutritional status score to predict prognosis after surgery in patients with resectable gastric cancer.

Xinghao Ma, Xiaoyang Jiang, Hao Guo, Jiajia Wang, Tingting Wang, Jiahu Yao, Song Liang, Xiuming Lu, Chuanxia Wang, Chuansi Wang

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinghao Ma *Department of Clinical Nutrition, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Xiaoyang Jiang *Department of Clinical Nutrition, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Hao GuoDepartment of Nutrition, School of Public Health, Anhui Medical University, NO. 81 of Meishan Road, Shushan District, Hefei, 230032, China.
Jiajia WangDepartment of Clinical Nutrition, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Tingting WangDepartment of Clinical Nutrition, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Jiahu YaoDepartment of General Surgery, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Song LiangDepartment of General Surgery, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Xiuming LuDepartment of General Surgery, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Chuanxia WangDepartment of Clinical Nutrition, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China.
Chuansi WangDepartment of General Surgery, Lu'an Hospital, Anhui Medical University, NO. 21 of Wanxi West Road, Jin'an District, Lu'an, 237005, China. chuansiwang@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious studies have shown that the controlling nutritional status (CONUT) score contributes to assessing the prognosis of cancer patients. This study aimed to establish a nomogram based on the CONUT score and several other important parameters based on patient age and tumor characteristics to accurately forecast the overall survival (OS) of patients with resectable gastric cancer (GC).

methodsThis study retrospectively recruited 404 individuals who received a potentially curative radical gastrectomy performed by the same group of surgeons at our medical center from January 2019 to December 2021. We used Cox regression analysis to identify independent prognostic factors influencing patients' OS. We establish a nomogram based on the outcomes of the multivariate analysis to forecast the 1, 2, and 3-year OS of GC patients.

resultsUnivariate Cox regression analysis revealed that the age, body mass index (BMI), hemoglobin (HGB), serum albumin (ALB), Serum carcinoembryonic antigen (CEA), CONUT score, tumor size, pT stage, pN stage, nerve invasion, vascular invasion, tumor differentiation, and postoperative chemotherapy were prognostic indicators of postoperative OS in GC patients (all P < 0.05). Multivariate Cox regression analysis indicated that the age (P = 0.015), CONUT score (P = 0.002), pT stage (T3 vs T1: P = 0.011, T4 vs T1: P = 0.026), pN stage (N2 vs N0: P = 0.002, N3 vs N0: P < 0.001), nerve invasion (P = 0.021) were the independent risk factors. The nomogram based on the CONUT score, with a C-index of 0.792, enhanced the predictive ability of the TNM staging system alone, which had a C-index of 0.718 for OS.

conclusionThe CONUT score can independently predict the OS for individuals with GC following surgery. The nomogram based on the CONUT score is a reliable tool for forecasting the postoperative survival of individuals with GC and may identify those patients wholesale benefit from a more aggressive treatment protocol.

Indexed as

GastrectomyNomogramsNutritional StatusStomach NeoplasmsAdultAgedAge FactorsBody Mass IndexCarcinoembryonic AntigenFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisProportional Hazards ModelsCarcinoembryonic AntigenSerum AlbuminCONUTGastric cancerNomogramPrognosisSurgery

Identifiers

PMID40097940
PMCPMC11916987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.