Evidence map›Paper›PMID 40097906›Full record

ArticleCell proliferation2025

YTHDC1 Modulates the Osteogenic Capacity of hPDLSCs via Wnt/β-Catenin Signalling Pathway for the Treatment of Bone Defects in Osteoporosis Rats.

Dan Tan, Qilin Li, Zhenzhen Chen, Hongbing Zhang, Pengcheng Rao, Jingxiang Li, Qianke Tao, Jingang Xiao, Jinlin Song

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell proliferation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. mStem cell research & therapy · 2026
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dan TanChongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, College of Stomatology of Chongqing Medical University, Chongqing, China.
Qilin LiLuzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, the Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, China.
Zhenzhen ChenDepartment of Oral Implantology, the Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, China.
Hongbing ZhangLuzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, the Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, China.
Pengcheng RaoLuzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, the Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, China.
Jingxiang LiLuzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, the Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, China.
Qianke TaoLuzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, the Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, China.
Jingang XiaoLuzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, the Affiliated Stomatological Hospital, Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0000-0003-1300-7191
Jinlin SongChongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, College of Stomatology of Chongqing Medical University, Chongqing, China.

Funding

2023 Key project of the Stomatological Hospital Affiliated to Southwest Medical University 2023Z02Foundation for Innovative Research Groups of the National Natural Science Foundation of China 82370938Project of Science & Technology Department of Sichuan Province 2024NSFSC2087Scientific and Technological Project of Luzhou 2022-JYJ-107Special Project for Local Science and Technology Development Guided by the Central Government of Sichuan Province 2022ZYD0082
6 · The paper itself

Abstract

Human periodontal ligament stem cells (hPDLSCs) have emerged as promising candidates for the treatment of osteoporotic bone defects. Previous studies have indicated that m

Indexed as

OsteogenesisOsteoporosisPeriodontal LigamentRNA-Binding ProteinsStem CellsWnt Signaling PathwayAnimalsbeta CateninCell DifferentiationCells, CulturedFemaleHumansIntercellular Signaling Peptides and ProteinsMaleRatsRats, Sprague-Dawleybeta CateninIntercellular Signaling Peptides and ProteinsRNA-Binding Proteinsbone regenerationhPDLSCsN6‐methyladenosineWnt/β‐catenin signalling pathwayYTHDC1

Identifiers

PMID40097906
PMCPMC12336452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.