Evidence map›Paper›PMID 40097783›Full record

ReviewNature genetics2025

The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project.

Lingzhao Fang, Jinyan Teng, Qing Lin, Zhonghao Bai, Shuli Liu, Dailu Guan, Bingjie Li, Yahui Gao, Yali Hou, Mian Gong and 125 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Special Issue "Bioinformatics of Gene Regulations and Structure-2025".International journal of molecular sciences · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Review
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. OmicsPred as a centralised resource for genetic prediction of multi-omic traits.medRxiv : the preprint server for health sciences · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Multi-Tissue Genetic Regulation of RNA Editing in Pigs.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

135 authors.

Lingzhao FangCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark. lingzhao.fang@qgg.au.dk.ORCID http://orcid.org/0000-0003-1103-3679
Jinyan TengState Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, China.ORCID http://orcid.org/0000-0002-3046-1452
Qing LinCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.
Zhonghao BaiCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.
Shuli LiuWestlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.
Dailu GuanDepartment of Animal Science, University of California, Davis, Davis, CA, USA.ORCID http://orcid.org/0000-0001-8800-3158
Bingjie LiDepartment of Animal and Veterinary Sciences, Scotland's Rural College, Midlothian, UK.ORCID http://orcid.org/0000-0002-8528-1889
Yahui GaoState Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, China.
Yali HouInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Mian GongCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-1785-0621
Zhangyuan PanInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Ying YuNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0002-4524-0791
Emily L ClarkThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, UK.
Jacqueline SmithThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, UK.ORCID http://orcid.org/0000-0002-2813-7872
Konrad RawlikBaillie Gifford Pandemic Science Hub, Centre for Inflammation Research, Institute for Regeneration and Repair, the University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-0010-370X
Ruidong XiangAgriculture Victoria Research, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.ORCID http://orcid.org/0000-0002-1584-7605
Amanda J ChamberlainAgriculture Victoria Research, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.ORCID http://orcid.org/0000-0002-9395-1299
Michael E GoddardAgriculture Victoria Research, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia.
Mathew LittlejohnResearch and Development, Livestock Improvement Corporation, Hamilton, New Zealand.
Greger LarsonThe Palaeogenomics and Bio-Archaeology Research Network, School of Archaeology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-4092-0392
David E MacHughUCD School of Agriculture and Food Science, University College Dublin, Belfield, Dublin, Ireland.ORCID http://orcid.org/0000-0002-8112-4704
John F O'GradyUCD School of Agriculture and Food Science, University College Dublin, Belfield, Dublin, Ireland.
Peter SørensenCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.
Goutam SahanaCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0001-7608-7577
Mogens Sandø LundCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.
Zhihua JiangDepartment of Animal Sciences and Center for Reproductive Biology, Washington State University, Pullman, WA, USA.ORCID http://orcid.org/0000-0003-1986-088X
Xiangchun PanState Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, China.
Wentao GongState Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, China.
Haihan ZhangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Xi HeCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Yuebo ZhangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Ning GaoCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Jun HeCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Guoqiang YiShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.ORCID http://orcid.org/0000-0001-8248-9126
Yuwen LiuShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.ORCID http://orcid.org/0009-0001-0470-2355
Zhonglin TangShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.ORCID http://orcid.org/0000-0002-4538-4349
Pengju ZhaoHainan Institute, Zhejiang University, Yongyou Industry Park, Yazhou Bay Sci-Tech City, Sanya, China.
Yang ZhouKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, Huazhong Agricultural University, Wuhan, China.
Liangliang FuKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, Huazhong Agricultural University, Wuhan, China.
Xiao WangInstitute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China.ORCID http://orcid.org/0000-0002-6192-3170
Dan HaoPoultry Institute, Shandong Academy of Agricultural Sciences, Jinan, China.
Lei LiuYazhouwan National Laboratory, Sanya, China.
Siqian ChenNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Robert S YoungUsher Institute, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-8300-8002
Xia ShenUsher Institute, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-4390-1979
Charley XiaLothian Birth Cohort studies, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-8194-9351
Hao ChengDepartment of Animal Science, University of California, Davis, Davis, CA, USA.
Li MaDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD, USA.ORCID http://orcid.org/0000-0003-1038-1081
John B ColeCouncil on Dairy Cattle Breeding, Bowie, MD, USA.ORCID http://orcid.org/0000-0003-1242-4401
Ransom L BaldwinAnimal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, MD, USA.ORCID http://orcid.org/0000-0002-0753-4377
Cong-Jun LiAnimal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, MD, USA.ORCID http://orcid.org/0000-0003-1389-9820
Curtis P Van TassellAnimal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, MD, USA.ORCID http://orcid.org/0000-0002-8416-2087
Benjamin D RosenAnimal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, MD, USA.ORCID http://orcid.org/0000-0001-9395-8346
Nayan BhowmikAnimal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, MD, USA.ORCID http://orcid.org/0000-0003-3906-1460
Joan LunneyAnimal Parasitic Diseases Laboratory, BARC, NEA, ARS, USDA, Beltsville, MD, USA.ORCID http://orcid.org/0000-0002-1147-8662
Wansheng LiuDepartment of Animal Science, Center for Reproductive Biology and Health, College of Agricultural Sciences, the Pennsylvania State University, University Park, PA, USA.ORCID http://orcid.org/0000-0003-1788-7093
Leluo GuanDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
Xin ZhaoDepartment of Animal Science, McGill University, Sainte-Anne-de-Bellevue, Quebec, Canada.ORCID http://orcid.org/0000-0002-1078-7332
Eveline M Ibeagha-AwemuSherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, Sherbrooke, Quebec, Canada.ORCID http://orcid.org/0000-0001-8810-9294
Yonglun LuoDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-0007-7759
Lin LinDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-7546-4948
Oriol Canela-XandriMRC Human Genetics Unit at the Institute of Genetics and Cancer, the University of Edinburgh, Edinburgh, UK.
Martijn F L DerksAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, the Netherlands.
Richard P M A CrooijmansAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, the Netherlands.
Marta GòdiaAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, the Netherlands.
Ole MadsenAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, the Netherlands.
Martien A M GroenenAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, the Netherlands.ORCID http://orcid.org/0000-0003-0484-4545
James E KoltesDepartment of Animal Science, Iowa State University, Ames, IA, USA.ORCID http://orcid.org/0000-0003-1897-5685
Christopher K TuggleDepartment of Animal Science, Iowa State University, Ames, IA, USA.ORCID http://orcid.org/0000-0002-4229-5316
Fiona M McCarthyUniversity of Arizona, Tucson, AZ, USA.
Dominique RochaGABI, AgroParisTech, INRAE, Paris-Saclay University, Jouy-en-Josas, France.
Elisabetta GiuffraGABI, AgroParisTech, INRAE, Paris-Saclay University, Jouy-en-Josas, France.ORCID http://orcid.org/0000-0001-9568-2056
Marcel AmillsDepartment of Animal Genetics, Centre for Research in Agricultural Genomics, CSIC-IRTA-UAB-UB, Campus de la Universitat Autònoma de Barcelona, Bellaterra, Spain.ORCID http://orcid.org/0000-0002-8999-0770
Alex ClopDepartment of Animal Genetics, Centre for Research in Agricultural Genomics, CSIC-IRTA-UAB-UB, Campus de la Universitat Autònoma de Barcelona, Bellaterra, Spain.ORCID http://orcid.org/0000-0001-9238-2728
Maria BallesterAnimal Breeding and Genetics Programme, Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Torre Marimon, Caldes de Montbui, Spain.ORCID http://orcid.org/0000-0002-5413-4640
Gwenola Tosser-KloppGenPhySE, INRAE, ENVT, Université de Toulouse, Castanet-Tolosan, France.ORCID http://orcid.org/0000-0003-0550-4673
Jing LiCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.
Chao FangLC-Bio Technologies, Co., Ltd, Hangzhou, China.
Ming FangKey Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture and Rural Affairs, Jimei University, Xiamen, China.ORCID http://orcid.org/0000-0003-3066-4855
Qishan WangCollege of Animal Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-6475-0009
Zhuocheng HouNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0003-4752-2255
Qin WangNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Fuping ZhaoInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID http://orcid.org/0000-0001-9582-5993
Lin JiangInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID http://orcid.org/0000-0001-9123-5988
Guiping ZhaoInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-1510-6903
Zhengkui ZhouInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-5192-2465
Rong ZhouInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID http://orcid.org/0000-0001-6579-2641
Hehe LiuCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
Juan DengCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
Long JinCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.ORCID http://orcid.org/0000-0002-6055-4692
Mingzhou LiCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.ORCID http://orcid.org/0000-0001-8681-7684
Delin MoState Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.ORCID http://orcid.org/0000-0002-8738-4486
Xiaohong LiuState Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Yaosheng ChenState Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Xiaolong YuanState Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, China.
Jiaqi LiState Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, China.
Shuhong ZhaoKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, Huazhong Agricultural University, Wuhan, China.ORCID http://orcid.org/0000-0002-3997-2320
Yi ZhangNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Xiangdong DingNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Dongxiao SunNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Hui-Zeng SunKey Laboratory of Dairy Cow Genetic Improvement and Milk Quality Research of Zhejiang Province, College of Animal Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0001-5380-6030
Cong LiCollege of Animal Science and Technology, Northwest A&F University, Yangling, China.
Yu WangCollege of Animal Science and Technology, Northwest A&F University, Yangling, China.
Yu JiangCollege of Animal Science and Technology, Northwest A&F University, Yangling, China.ORCID http://orcid.org/0000-0003-4821-3585
Dongdong WuKey Laboratory of Genetic Evolution and Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.ORCID http://orcid.org/0000-0001-7101-7297
Wenwen WangShandong Provincial Key Laboratory for Livestock Germplasm Innovation and Utilization, College of Animal Science, Shandong Agricultural University, Tai'an, China.
Xinzhong FanShandong Provincial Key Laboratory for Livestock Germplasm Innovation and Utilization, College of Animal Science, Shandong Agricultural University, Tai'an, China.
Qin ZhangShandong Provincial Key Laboratory for Livestock Germplasm Innovation and Utilization, College of Animal Science, Shandong Agricultural University, Tai'an, China.
Kui LiShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.ORCID http://orcid.org/0000-0002-5686-3898
Hao ZhangNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Ning YangNational Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0001-5772-3320
Xiaoxiang HuState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0001-7045-0283
Wen HuangDepartment of Animal Science, Michigan State University, East Lansing, MI, USA.ORCID http://orcid.org/0000-0001-6788-8364
Jiuzhou SongDepartment of Animal and Avian Sciences, University of Maryland, College Park, MD, USA.
Yang WuInstitute of Rare Diseases, West China Hospital of Sichuan University, Chengdu, China.
Jian YangWestlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.ORCID http://orcid.org/0000-0003-2001-2474
Weiwei WuInstitute of Animal Science, Xinjiang Academy of Animal Science, Ürümqi City, China.
Claudia KasperAnimal GenoPhenomics, Animal Production Systems and Animal Health, Agroscope Posieux, Fribourg, Switzerland.ORCID http://orcid.org/0000-0001-7305-3996
Xinfeng LiuCenter for Quantitative Genetics and Genomics, Aarhus University, Aarhus, Denmark.
Xiaofei YuCollege of Marine Life Sciences, Ocean University of China, Qingdao, China.
Leilei CuiSchool of Life Sciences, Nanchang University, Nanchang, China.
Xiang ZhouDepartment of Biostatistics, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-4331-7599
Seyoung KimDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Wei LiDivision of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA, USA.ORCID http://orcid.org/0000-0001-9931-5990
Hae Kyung ImDepartment of Medicine and Human Genetics, the University of Chicago, Chicago, IL, USA.
Edward S BucklerSection of Plant Breeding and Genetics, Cornell University, Ithaca, NY, USA.ORCID http://orcid.org/0000-0002-3100-371X
Bing RenDepartment of Cellular and Molecular Medicine, Center for Epigenomics, Moores Cancer Center and Institute of Genomic Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-5435-1127
Michael C SchatzDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-4118-4446
Jingyi Jessica LiDepartment of Statistics and Data Science, University of California, Los Angeles, Los Angeles, CA, USA. lijy03@g.ucla.edu.ORCID http://orcid.org/0000-0002-9288-5648
Abraham A PalmerDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA. aap@ucsd.edu.ORCID http://orcid.org/0000-0003-3634-0747
Laurent FrantzPalaeogenomics Group, Institute of Palaeoanatomy, Domestication Research and the History of Veterinary Medicine, Ludwig-Maximilians-Universität, Munich, Germany. laurent.frantz@lmu.de.ORCID http://orcid.org/0000-0001-8030-3885
Huaijun ZhouDepartment of Animal Science, University of California, Davis, Davis, CA, USA. hzhou@ucdavis.edu.ORCID http://orcid.org/0000-0001-6023-9521
Zhe ZhangState Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, China. zhezhang@scau.edu.cn.ORCID http://orcid.org/0000-0001-7338-7718
George E LiuAnimal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, MD, USA. george.liu@usda.gov.ORCID http://orcid.org/0000-0003-0192-6705
FarmGTEx Consortium

Funding

SHAPEIT+Salmon: haplotype phasing and RNA-seq quantification for allele-specific eQTL mappingR21HG011116 · NHGRI · CARNEGIE-MELLON UNIVERSITY · PI KIM, SEYOUNG · 2020 to 2021
$383k
Statistical Approach to Uncovering Gene Networks Perturbed by Cis-acting and Trans-acting eQTLswith Active LearningR21HG010948 · NHGRI · CARNEGIE-MELLON UNIVERSITY · PI KIM, SEYOUNG · 2020 to 2020
$377k
NHGRI NIH HHS R21 HG010948NHGRI NIH HHS R21 HG011116
6 · The paper itself

Abstract

Genetic mutation and drift, coupled with natural and human-mediated selection and migration, have produced a wide variety of genotypes and phenotypes in farmed animals. We here introduce the Farm Animal Genotype-Tissue Expression (FarmGTEx) Project, which aims to elucidate the genetic determinants of gene expression across 16 terrestrial and aquatic domestic species under diverse biological and environmental contexts. For each species, we aim to collect multiomics data, particularly genomics and transcriptomics, from 50 tissues of 1,000 healthy adults and 200 additional animals representing a specific context. This Perspective provides an overview of the priorities of FarmGTEx and advocates for coordinated strategies of data analysis and resource-sharing initiatives. FarmGTEx aims to serve as a platform for investigating context-specific regulatory effects, which will deepen our understanding of molecular mechanisms underlying complex phenotypes. The knowledge and insights provided by FarmGTEx will contribute to improving sustainable agriculture-based food systems, comparative biology and eventual human biomedicine.

Indexed as

Animals, DomesticAnimalsGenomicsGenotypeHumansPhenotypeTranscriptome

Identifiers

PMID40097783

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