Evidence map›Paper›PMID 40097746›Full record

ArticleInternational urology and nephrology2025

Relationship between anogenital distance and testicular position in male infants with cryptorchidism with and without hypospadias.

Salah Nagla, Shaymaa Elrifaey, Hend Abdelnabi, Ayman Hagras, Ahmed Arafa, Mohamed Hamza, Waleed Dawood

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Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Salah NaglaUrology Department, Faculty of Medicine, Tanta University, Tanta, Egypt. salahnaglah@yahoo.com.ORCID http://orcid.org/0000-0003-2345-9853
Shaymaa ElrifaeyDepartment of Pediatrics, Faculty of Medicine, Tanta University, Tanta, Egypt.
Hend AbdelnabiDepartment of Pediatrics, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ayman HagrasUrology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ahmed ArafaDepartment of Pediatrics, Faculty of Medicine, Tanta University, Tanta, Egypt.
Mohamed HamzaDepartment of Pediatrics, Faculty of Medicine, Tanta University, Tanta, Egypt.
Waleed DawoodUrology Department, Alexandria University, Alexandria, Egypt.

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6 · The paper itself

Abstract

purposeAnogenital distance (AGD) may indicate hypoverilization and subsequently serve as a predictor future reproduction. In both undescended testis with and without hypospadias, our goal was to study the relationship between testicular position and AGD.

methodsFrom March 2021 to January 2023, this study was conducted on male infants with and without hypospadias and age-matched controls. Based on the infants' ages, we divided them into four. Group I: under six months, Group II: 7-12 months, Group III: between a year and eighteen months, and Group IV: 19 months up to two years of age. From the verge of the anus to the penile base, the AGD was measured. Clinical examination resulted in the classification of testicular location as high scrotal, inguinal, and non-palpable.

resultsPatients with cryptorchidism had AGD means that were substantially lower than those of controls in Groups I, II, III, and IV, respectively (31 ± 2, 33 ± 3), (35.9 ± 4, 37.9 ± 5), (39.9 ± 1.2, 41 ± 1.5), and (40 ± 1.9, 44 ± 1.7). The group of patients with cryptorchidism and hypospadias differed significantly from the controls and those without hypospadias. AGD in patients with upper scrotal locations was substantially shorter. Penile length and AGD of the examined groups exhibited a positive and significant connection.

conclusionsShorter AGD is linked to a higher prevalence of hypospadias and cryptorchidism in male babies in comparison to normal children. The position of the undescended testis is higher in relation to a shorter AGD.

Indexed as

Anal CanalCryptorchidismHypospadiasTestisCase-Control StudiesChild, PreschoolHumansInfantMalePenisAnogenital distanceCryptorchidismHypospadias

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.