Evidence map›Paper›PMID 40097745›Full record

ArticleEye (London, England)2025

Clinical characteristics of dome-shaped macula in mild myopic or non-myopic eyes.

Mengyang Li, Zhi Li, Fei Xiang, Caixia Li, Ye Zhang, Shuning Li

Abstract read
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mengyang LiBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0002-9687-6458
Zhi LiBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Capital Medical University, Beijing, China.
Fei XiangBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Capital Medical University, Beijing, China.
Caixia LiShaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, China.ORCID http://orcid.org/0009-0002-3008-6717
Ye ZhangBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0001-5775-125X
Shuning LiBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Capital Medical University, Beijing, China. lishuningqd@163.com.ORCID http://orcid.org/0000-0002-6233-5549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate dome-shaped macula (DSM) in mild myopic or non-myopic eyes.

methodsParticipants aged 50 years or older were recruited from July 2023 to August 2023. Clinical features including age, sex, visual acuity (VA), spherical equivalent refraction (SER), ocular biometry parameters, SS-OCT parameters and macular complications were compared between eyes with and without DSM. Logistic analysis was performed to explore risk factors for DSM.

results923 eyes were enrolled in the final analysis. The overall prevalence of DSM was 3.03% (28/923). Among eyes with DSM, 13 eyes (46.4%) were emmetropia, 9 eyes (32.1%) were hypermetropia, and 6 eyes (21.4%) were myopia, with 4 eyes (14.3%) were mild myopia and one eye (3.6%) was moderate myopia. The mean subfoveal choroidal thickness (SFCT) in eyes with DSM was 168.00 ± 77.79μm, which was significantly thinner than their counterparts absent of DSM (289.11 ± 95.58μm, p < 0.001). Logistic regression revealed that longer AL (odds ratio (OR) = 1.716, 95%CI: 1.205-2.442, p = 0.003) and female sex (OR = 3.330, 95% CI: 1.109-10.005, p = 0.032) were associated with DSM. No vitreomacular complication including epiretinal membrane (ERM), vitreomacular traction (VMT), lamellar macular hole (LMH) and full-thickness macular hole (FTMH) was found in eyes with DSM, while the overall prevalence of those macular complications in eye without DSM was 8.8% (79/895).

conclusionsThe study offered a detailed profile of DSM in mild myopic or non-myopic eyes and found a diffuse thinning of choroid in both foveal and parafoveal area in eyes with DSM. No case with vitreomacular complications was identified in DSM eyes in our study population. TRAIL REGISTRATION: The registration number of the present trial in the Chinese Clinical Trial Registry is ChiCTR2000037944.

Indexed as

Macula LuteaMyopiaRetinal DiseasesAgedFemaleHumansMaleMiddle AgedPrevalenceRefraction, OcularRisk FactorsTomography, Optical CoherenceVisual Acuity

Identifiers

PMID40097745
PMCPMC12130301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.