Evidence map›Paper›PMID 40097534›Full record

ArticleScientific reports2025

Global burden of malaria before and after the COVID-19 pandemic based on the global burden of disease study 2021.

Jiaofeng Huang, Yuekai Hu, Yinlian Wu, Li Pan, Mingfang Wang, Wei Wang, Su Lin

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaofeng Huang *Department of Hepatology, Hepatology Research Institute, Fujian Clinical Research Center for Liver and Intestinal Diseases, The First Affiliated Hospital, Fujian Medical University, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350002, Fujian Province, China.
Yuekai Hu *Department of Infectious Diseases, National Medical Center for Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200040, China.
Yinlian WuDepartment of Hepatology, Hepatology Research Institute, Fujian Clinical Research Center for Liver and Intestinal Diseases, The First Affiliated Hospital, Fujian Medical University, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350002, Fujian Province, China.
Li PanNational Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, No. 117 Meiyuan, Yangxiang, Wuxi, 214064, Jiangsu Province, China.
Mingfang WangDepartment of Hepatology, Hepatology Research Institute, Fujian Clinical Research Center for Liver and Intestinal Diseases, The First Affiliated Hospital, Fujian Medical University, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350002, Fujian Province, China.
Wei WangNational Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, No. 117 Meiyuan, Yangxiang, Wuxi, 214064, Jiangsu Province, China. wangwei@jipd.com.
Su LinDepartment of Hepatology, Hepatology Research Institute, Fujian Clinical Research Center for Liver and Intestinal Diseases, The First Affiliated Hospital, Fujian Medical University, No. 20, Chazhong Road, Taijiang District, Fuzhou, 350002, Fujian Province, China. sumer5129@fjmu.edu.cn.

Funding

National Natural Science Foundation of China 82300652
6 · The paper itself

Abstract

Malaria poses significant public health challenges and huge disease and economic burdens across the world, notably in low-income countries. Although great strides have been achieved, the COVID-19 pandemic hinders the progress towards global elimination of malaria. This study utilizes data from the global burden of disease study 2021 data sources to assess trends in incidence and mortality of, and disability-adjusted life years (DALYs) lost due to malaria before and after the global COVID-19 pandemic, and projects the incidence of malaria in 2030 at international, regional and national levels. The age-standardized incidence of malaria declined from 3789.28 per 100,000 populations in 2010 to 3332.96 per 100,000 population in 2019, followed by a rapid increase to 3485.27 per 100,000 populations in 2021. The estimated annual percentage change was 2.26% (95% confidence interval: 1.84-2.68%) from 2019 to 2021, suggesting a significant acceleration in the increasing rate compared to previous years. The numbers of DALYs lost and death due to malaria also increased in 2021. Children under 5 years of age and regions with low socio-demographic index were disproportionately affected with the highest burden of malaria associated with the COVID-19 pandemic. The pandemic is projected to lead to an additional 472.59 malaria cases per 100,000 populations by 2030. The global COVID-19 pandemic has posed substantial challenges to the global malaria elimination program as revealed by increasing incidence, death and DALYs lost across the world.

Indexed as

COVID-19Global Burden of DiseaseMalariaAdolescentAdultAgedChildChild, PreschoolDisability-Adjusted Life YearsFemaleGlobal HealthHumansIncidenceInfantInfant, NewbornMaleBurden of diseaseCOVID-19GBDMalaria

Identifiers

PMID40097534
PMCPMC11914637

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.