ArticleScientific reports2025
Phase-lagged tACS between executive and default mode networks modulates working memory.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Bifocal Beta-frequency Transcranial Alternating Current Stimulation Enhances Somatosensory Spatial Discrimination.Brain topography · 2026Article
- Network-nodal tACS induces right-lateralization of thalamocortical connectivity.Scientific reports · 2026Article
- Neuromodulation of Working Memory: Mechanisms, Targets, and Behavioral Outcomes.Neuroscience insights · 2026Review
- Transcranial alternating current stimulation improves cognitive functions in healthy subjects through modifying frontoparietal and dorsal attention networks based on personalized individual theta frequency analysis.Frontiers in behavioral neuroscience · 2026Article
- Deep learning-based electroencephalic decoding of the phase-lagged transcranial alternating current stimulation.Frontiers in human neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Transcranial alternating current stimulation (tACS) is an efficient neuromodulation technique to enhance cognitive function in a non-invasive manner. Using functional magnetic resonance imaging, we investigated whether a cross-frequency coupled tACS protocol with a phase lag (45 and 180 degrees) between the central executive and the default mode networks modulated working-memory performance. We found tACS-phase-dependent modulation of task performance reflected in hippocampal activation and task-related functional connectivity. Our observations provide a neurophysiological basis for neuromodulation and a feasible non-invasive approach to selectively stimulate a task-relevant deep brain structure. Overall, our study highlights the potential of tACS as a powerful tool for enhancing cognitive function and sheds light on the underlying mechanisms of this technique.
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Registered trials
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