ArticleLa Tunisie medicale2025
Agenesis of the Dorsal Pancreas: An Uncommon Cause of Pancreatic Diabetes in Young Adults. A Case Report.
Article in La Tunisie medicale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionAgenesis of the dorsal pancreas (ADP) is a rare congenital abnormality characterized by the absence of the body and tail of the pancreas. This condition is often asymptomatic. While many patients exhibit nonspecific symptoms, some may experience more severe manifestations complicating the diagnostic process. OBSERVATION: We presented the case of a 27-year-old man who was diagnosed with type 1 diabetes mellitus three years ago. He was experiencing considerable weight loss, abdominal pain, and diarrhea despite effectively managed insulin therapy. The patient appeared emaciated and malnourished. Investigations revealed a normal thyroid function, negative celiac disease serology, and negative pancreatic antibodies. Abdominal imaging demonstrated ADP. After treatment with insulin and pancreatic enzymes, we noted a significant improvement in the patient's condition.
conclusionThis case emphasizes diagnostic challenges in young patients presenting with pancreatic diabetes. Early recognition and appropriate management are crucial to prevent complications of both exocrine and endocrine deficiencies.
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