Evidence map›Paper›PMID 40096732›Full record

ArticleLa Tunisie medicale2025

Nadia Romdhane, Dorra Chiboub, Amira Khaldi, Jihene Gharsalli, Imen Zoghlami, Safa Nefzaoui, Ines Hariga, Chiraz Mbarek

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in La Tunisie medicale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nadia RomdhaneENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Dorra ChiboubENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Amira KhaldiENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Jihene GharsalliENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Imen ZoghlamiENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Safa NefzaouiENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Ines HarigaENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.
Chiraz MbarekENT and Head and Neck Surgery Department, Habib Thamer Hospital, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-invasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) still spark controversy regarding histological diagnostic criteria and therapeutic management.

aimTo elucidate the clinicopathological characteristics of NIFTP tumors and discuss their therapeutic management.

methodsA retrospective study including 23 patients (26 nodules) operated on and followed up for NIFTP tumors according to the 2017 WHO classification over a 5-year period (January 2016-December 2020). The 2017 EUTIRADS classification was used for ultrasound nodule characterization. Fine-needle aspiration cytology was reported according to the 2017 Bethesda system.

resultsAll patients were female, with a mean age of 47 years [19-71]. The average consultation delay was 9 months [2 months-7 years]. Thyroid nodules were incidentally discovered in 6 cases (26%). Examination revealed a solitary thyroid nodule in 20 cases. Nodules were classified as EUTIRADS III or IV in 82%. Fine-needle aspiration cytology, performed in 61% of cases, showed Bethesda III in 64% and IV in 14%. Total thyroidectomy was performed in 74%. Three cases of bifocal NIFTP were identified. Association with thyroid carcinoma was noted in 7 cases. No locoregional or distant recurrence was reported during a mean follow-up of 3 and a half years.

conclusionRecent revisions of NIFTP morphological criteria underscore the importance of strict adherence to inclusion and exclusion histo-morphological criteria.

Indexed as

Adenocarcinoma, FollicularThyroid NeoplasmsAdultAgedBiopsy, Fine-NeedleFemaleHumansMiddle AgedRetrospective StudiesThyroid Cancer, PapillaryThyroidectomyThyroid NoduleYoung Adultfine needle aspirationNIFTPsurgeryThyroid tumorultrasound

Identifiers

PMID40096732
PMCPMC12034351

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.