Evidence map›Paper›PMID 40096730›Full record

Observational studyLa Tunisie medicale2025

Mahmoud Marzouk, Aymen Adhoum, Azza Ben Yedder, Rabeb Hammami, Saber Thamlaoui, Nader Baffoun

Abstract readObservational StudyEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Observational study in La Tunisie medicale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahmoud MarzoukDepartment of Anaesthesia and Intensive Care, National Institute of Neurology of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Aymen AdhoumDepartment of Anaesthesia and Intensive Care, National Institute of Neurology of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Azza Ben YedderDepartment of Anaesthesia and Intensive Care, National Institute of Neurology of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Rabeb HammamiDepartment of Anaesthesia and Intensive Care, National Institute of Neurology of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Saber ThamlaouiDepartment of Anaesthesia and Intensive Care, National Institute of Neurology of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Nader BaffounDepartment of Anaesthesia and Intensive Care, National Institute of Neurology of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute kidney Injury (AKI) is the most frequent complication of septic shock. Bedside ultrasound measurement of the renal resistance index (RRI) is an interesting way of assessment of renal hemodynamics.

aimsTo study the variability of RRI during septic shock and its correlation with the occurrence of AKI.

methodsThis is a prospective observational study including patients in septic shock and on mechanical ventilation. Data collection was carried out between October 2022 and July 2023. RRI was measured during the first five days of shock.

resultsForty patients were enrolled in the study. Mean age was equal to 51 years ±13.4 and sex ratio was equal to 2.33. The mean RRI value was 0.704, with extremes ranging from 0.52 to 0.83. Patients were divided into two groups : AKI(+) and AKI (-). RRI in the group AKI (+) was higher than in the group AKI (-) (0.757 vs. 0.672; p=0.013). RRI predicted the occurrence of AKI, with an area under the ROC curve of 0.75 (p=0.007) and a cut-off value of 0.71 (specificity=64%, sensitivity=73%).

conclusionAssessment of RRI could be a useful technique of predicting the onset of AKI in association with the conventional markers. Its validation will guide management towards optimal renal protection in patients with septic shock.

Indexed as

Acute Kidney InjuryKidneyShock, SepticVascular ResistanceAdultAgedFemaleHumansMaleMiddle AgedPoint-of-Care TestingProspective StudiesRespiration, ArtificialROC CurveSensitivity and SpecificityUltrasonographyAcute kidney injuryCreatinineDiuresisSeptic shockUltrasoundVascular resistance

Identifiers

PMID40096730
PMCPMC12034352

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.