Evidence map›Paper›PMID 40096556›Full record

ArticleClinical journal of oncology nursing2025

Assessing Etoposide and Cyclophosphamide Contamination and Current Cleaning Practices in Patient Bathrooms.

AnnMarie L Walton, Margaret A Bush, Anthony D Sung, Melissa A Powell, Haesu J Jin, Susan G Silva, Ivan Spasojevic

Abstract read
In one paragraph

Article in Clinical journal of oncology nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

AnnMarie L WaltonAnnMarie L. Walton.
Margaret A BushMargaret A. Bush.
Anthony D SungAnthony D. Sung.
Melissa A PowellMelissa A. Powell.
Haesu J JinHaesu J. Jin.
Susan G SilvaSusan G. Silva.
Ivan SpasojevicIvan Spasojevic.

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8M
NCI NIH HHS P30 CA014236
6 · The paper itself

Abstract

backgroundAntineoplastic drug (AD) exposure presents severe risks to healthcare workers. Previous studies have demonstrated that patient bathrooms are highly contaminated and have led to concern for excreta as a source of environmental contamination with ADs.

objectivesThis study assessed AD contamination and current cleaning practices to remove AD surface contamination in patient bathrooms.

methodsThree surfaces in the bathrooms of patients who had received etoposide and/or cyclophosphamide were sampled and analyzed for contamination at three time points. Liquid chromatography-tandem mass spectrometry was used for analysis. Interviews and observations of daily and discharge cleaning were conducted to understand cleaning practices.

findingsA significant reduction in etoposide contamination on toilets and floors was observed following discharge cleaning; however, no significant reduction was observed on walls for either AD or on floors for cyclophosphamide.

Indexed as

Antineoplastic AgentsCyclophosphamideEquipment ContaminationEtoposideToilet FacilitiesAdultAgedFemaleHumansMaleMiddle AgedAntineoplastic AgentsCyclophosphamideEtoposideantineoplastic drugsexcretaoccupational exposuresurface contamination

Identifiers

PMID40096556
PMCPMC12056824

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.