Evidence map›Paper›PMID 40096545›Full record

Observational studyClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

Long-Acting Injectable HIV Therapy Outcomes Among Persons With HIV Who Have Adherence Challenges to Oral Antiretroviral Therapy.

Elizabeth Hastie, Lucas Hill, Laura Bamford, Afsana Karim, Thomas C S Martin

Abstract readObservational Study
In one paragraph

Observational study in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth HastieDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California-San Diego, San Diego, California, USA.ORCID 0000-0001-6587-6968
Lucas HillDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California-San Diego, San Diego, California, USA.
Laura BamfordDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California-San Diego, San Diego, California, USA.
Afsana KarimDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California-San Diego, San Diego, California, USA.
Thomas C S MartinDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California-San Diego, San Diego, California, USA.

Funding

HOPE Training GrantT32AI007384 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sara Gianella Weibel, Scott L Letendre · 1990 to 2026
$9.7M
NIAID NIH HHS T32 AI007384
6 · The paper itself

Abstract

Long-acting injectable cabotegravir/rilpivirine (LAI-CAB/RPV) may improve outcomes among persons with human immunodeficiency virus (PWH) with adherence difficulties to oral therapy. In this real-world observational study, over 85% of PWH remained on therapy and virally suppressed 48 weeks after initiating LAI-CAB/RPV. Providers should consider LAI therapy among PWH with adherence difficulties.

Indexed as

Anti-HIV AgentsHIV InfectionsMedication AdherencePyridonesRilpivirineAdministration, OralAdultDelayed-Action PreparationsDiketopiperazinesFemaleHumansInjectionsMaleMiddle AgedTreatment OutcomeViral LoadAnti-HIV AgentscabotegravirDelayed-Action PreparationsDiketopiperazinesPyridonesRilpivirineadherence challengescabotegravir-rilpivirinelong-acting injectablespeople with HIVviremia

Identifiers

PMID40096545
PMCPMC12497944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.