Evidence map›Paper›PMID 40096542›Full record

ArticleMagnetic resonance in medicine2025

Simultaneous 3D quantitative magnetization transfer imaging and susceptibility mapping.

Albert Jang, Kwok-Shing Chan, Azma Mareyam, Jason Stockmann, Susie Yi Huang, Nian Wang, Hyungseok Jang, Hong-Hsi Lee, Fang Liu

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Albert JangAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.ORCID 0000-0002-6375-4550
Kwok-Shing ChanAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.ORCID 0000-0001-8427-169X
Azma MareyamAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Jason StockmannAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.ORCID 0000-0001-8454-5347
Susie Yi HuangAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Nian WangBiomedical Engineering, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Hyungseok JangRadiology, University of California, Davis, Davis, California, USA.ORCID 0000-0002-3597-9525
Hong-Hsi LeeAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.ORCID 0000-0002-3663-6559
Fang LiuAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.ORCID 0000-0001-8032-6681

Funding

Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2020 to 2026
$10.9M
Deep Learning Technology for Rapid Morphological and Quantitative Imaging of Knee PathologyR01AR079442 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI Fang Liu · 2022 to 2026
$2.2M
Rapid Three-dimensional Simultaneous Knee Multi-Relaxation MappingR01AR081344 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI Fang Liu · 2022 to 2026
$2.0M
Deep Learning Reconstruction for Rapid Multi-Component RelaxometryR21EB031185 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI LIU, FANG · 2022 to 2024
$690k
Ultra-Fast High-Resolution Multi-Parametric MRI for Characterizing Cartilage Extracellular MatrixR56AR081017 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LIU, FANG · 2023 to 2023
$643k
NIAMS NIH HHS R01 AR079442NIAMS NIH HHS R01AR079442NIAMS NIH HHS R01 AR081344NIAMS NIH HHS R01AR081344NIAMS NIH HHS R56 AR081017NIAMS NIH HHS R56AR081017NIBIB NIH HHS P41 EB030006NIBIB NIH HHS R21 EB031185NIBIB NIH HHS R21EB031185ZonMw 04520232330012
6 · The paper itself

Abstract

purposeIntroduce a unified acquisition and modeling strategy to simultaneously quantify magnetization transfer (MT), tissue susceptibility ( THEORY AND

methodsMagnetization transfer is induced through the application of off-resonance irradiation between excitation and acquisition of an RF-spoiled gradient-echo scheme, where free pool spin-lattice relaxation (

resultsIn vivo brain experiments were conducted on five healthy subjects to validate our method. Utilizing an analytically derived signal model, we simultaneously obtained 3D

conclusionA unified acquisition and modeling strategy based on an analytical signal model that fully leverages both the magnitude and phase of the acquired signals was demonstrated and validated for simultaneous MT, susceptibility and

Indexed as

BrainImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingAdultAlgorithmsHumansMalePhantoms, ImagingReproducibility of Resultsmagnetization transferquantitative imagingquantitative susceptibility mappingtissue modeling

Identifiers

PMID40096542
PMCPMC12137784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.