Evidence map›Paper›PMID 40096166›Full record

ArticleTechnology in cancer research & treatment

Treatment Outcome of Brain Metastases from Breast Cancer Following Gamma Knife Radiosurgery: A Retrospective Study in Vietnam.

Huyen Thi Phung, Yen Thi Le, Tung Van Nguyen, Giang Tien Dang, Quang Hong Nguyen, Duong Thanh Phan, Hoa Thi Nguyen, Long Thanh Nguyen

Abstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huyen Thi PhungDepartment of Medical Oncology No. 6, Vietnam National Cancer Hospital, Hanoi, Vietnam.
Yen Thi LeDepartment of Quan Su Medical Oncology, Vietnam National Cancer Hospital, Hanoi, Vietnam.
Tung Van NguyenDepartment of Medical Oncology No. 6, Vietnam National Cancer Hospital, Hanoi, Vietnam.
Giang Tien DangDepartment of Medical Oncology No. 6, Vietnam National Cancer Hospital, Hanoi, Vietnam.ORCID 0009-0003-7454-9426
Quang Hong NguyenDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.ORCID 0009-0006-1044-1629
Duong Thanh PhanDepartment of Neurosurgery, Vietnam National Cancer Hospital, Hanoi, Vietnam.
Hoa Thi NguyenDepartment of Medical Oncology No. 6, Vietnam National Cancer Hospital, Hanoi, Vietnam.
Long Thanh NguyenDepartment of Medical Oncology No. 6, Vietnam National Cancer Hospital, Hanoi, Vietnam.ORCID 0000-0002-0601-1013

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundGamma Knife radiosurgery has proven to be highly effective for small brain lesions and those with a limited number of metastases. This study aimed to evaluate the treatment outcome of Gamma Knife radiosurgery in Vietnamese breast cancer patients with brain metastasis.MethodsThis retrospective descriptive study included 75 patients treated between January 2019 and December 2023. Eligible patients had 1 to 5 brain lesions ≤ 3 cm, a Karnofsky Performance Status (KPS) score of ≥ 60, and no prior whole-brain radiotherapy or brain tumor resection. Clinical characteristics were documented, and imaging responses were evaluated using RECIST criteria. Overall survival (OS), brain-specific progression-free survival (BSPFS), and overall response rates were analyzed using Kaplan-Meier survival curves and Cox regression.ResultsSeventy-five patients were included in the study, with a median follow-up time of 15.9 months. The median age was 53.0 years (range: 29-73 years), and 39 patients (52%) were HER2-positive. The median total tumor volume per patient was 3.78 cm

Indexed as

Brain NeoplasmsBreast NeoplasmsRadiosurgeryAdultAgedFemaleHumansKaplan-Meier EstimateMiddle AgedRetrospective StudiesTreatment OutcomeVietnambrain metastasisbreast cancerGamma KniferadiosurgerysurvivalVietnam

Identifiers

PMID40096166
PMCPMC11915535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.