Evidence map›Paper›PMID 40096108›Full record

SynthesisSensors (Basel, Switzerland)2025

Non-Invasive BCI-VR Applied Protocols as Intervention Paradigms on School-Aged Subjects with ASD: A Systematic Review.

Archondoula Alexopoulou, Pantelis Pergantis, Constantinos Koutsojannis, Vassilios Triantafillou, Athanasios Drigas

Abstract readSystematic Review
In one paragraph

Synthesis in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Archondoula AlexopoulouDepartment of Electrical and Computer Engineering, University of Patras, 26334 Patras, Greece.ORCID 0000-0002-2500-8709
Pantelis PergantisNet Media Lab & Mind & Brain R&D, Institute of Informatics & Telecommunications, National Centre of Scientific Research 'Demokritos', 15341 Agia Paraskevi, Greece.ORCID 0009-0003-7788-9338
Constantinos KoutsojannisHealth Physics & Computational Intelligence Lab, Physiotherapy Department, School of Health Rehabilitation Sciences, University of Patras, 25100 Patras, Greece.ORCID 0000-0003-2664-2127
Vassilios TriantafillouNetwork Technologies and Digital Transformation Lab, Electrical and Computer Engineering Department, University of Peloponnese, 26504 Patras, Greece.
Athanasios DrigasNet Media Lab & Mind & Brain R&D, Institute of Informatics & Telecommunications, National Centre of Scientific Research 'Demokritos', 15341 Agia Paraskevi, Greece.ORCID 0000-0001-5637-9601

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper aims to highlight non-invasive BCI-VR applied protocols as intervention paradigms on school-aged subjects with ASD. Computer-based interventions are considered appropriate for users with ASD as concentration on a screen reduces other stimuli from the environment that are likely to be distracting or disruptive. Since there are no social conditions for engagement in such processes and the responses of computing systems do not hold surprises for users, as the outputs are fully controlled, they are ideal for ASD subjects. Children and adolescents with ASD, when supported by BCI interventions through virtual reality applications, especially appear to show significant improvements in core symptoms, such as cognitive and social deficits, regardless of their age or IQ. We examined nine protocols applied from 2016 to 2023, focusing on the BCI paradigms, the procedure, and the outcomes. Our study is non-exhaustive but representative of the state of the art in the field. As concluded by the research, BCI-VR applied protocols have no side effects and are rather easy to handle and maintain, and despite the fact that there are research limitations, they hold promise as a tool for improving social and cognitive skills in school-aged individuals with ASD.

Indexed as

Autism Spectrum DisorderBrain-Computer InterfacesVirtual RealityAdolescentChildCognitionElectroencephalographyHumansMaleautism spectrum disorder (ASD)brain–computer interface (BCI)EEG signalsemotional regulationjoint attentionmemoryneurofeedback (NFT)social skillsvirtual reality (VR)

Identifiers

PMID40096108
PMCPMC11902634

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.