Evidence map›Paper›PMID 40095843›Full record

ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2025

Koopman-Based Model Predictive Control of Functional Electrical Stimulation for Ankle Dorsiflexion and Plantarflexion Assistance.

Mayank Singh, Noor Hakam, Trisha M Kesar, Nitin Sharma

Abstract read
In one paragraph

Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mayank Singh
Noor Hakam
Trisha M Kesar
Nitin Sharma

Funding

Innovative closed-loop functional electrical stimulation control system for augmenting post-stroke gaitR21HD116484 · NICHD · EMORY UNIVERSITY · PI KESAR, TRISHA, SHARMA, NITIN · 2024 to 2025
$418k
NICHD NIH HHS R21 HD116484
6 · The paper itself

Abstract

Functional Electrical Stimulation (FES) can be an effective tool to augment paretic muscle function and restore normal ankle function. Our approach incorporates a real-time, data-driven Model Predictive Control (MPC) scheme built upon a Koopman operator theory (KOT) framework. This framework adeptly captures the complex nonlinear dynamics of ankle motion in a linearized form, enabling the application of linear control approaches for highly nonlinear FES-actuated dynamics. Our method accurately predicts the FES-induced ankle movements, accounting for nonlinear muscle actuation dynamics, including the muscle activation for both plantarflexors and dorsiflexors (Tibialis Anterior (TA)). The linear prediction model derived through KOT allowed the formulation of the MPC problem with linear state space dynamics, enhancing the FES-driven control's real-time feasibility, precision, and adaptability. We demonstrate the effectiveness and applicability of our approach through comprehensive simulations and experimental trials, including three participants with no disability and a participant with Multiple Sclerosis. Our findings highlight the potential of a KOT-based MPC approach for FES-based gait assistance that offers effective and personalized assistance for individuals with gait impairment conditions.

Indexed as

AnkleAnkle JointElectric Stimulation TherapyAdultAlgorithmsComputer SimulationFemaleHumansMaleMiddle AgedModels, BiologicalMultiple SclerosisMuscle, SkeletalNonlinear DynamicsRange of Motion, Articular

Identifiers

PMID40095843
PMCPMC12103729

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.