Evidence map›Paper›PMID 40095718›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2025

Skeletal Rearrangements of Amides via Breaking Inert Bonds.

Rui Zhang, Guangbin Dong

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. "Cut-and-Sew" Reactions of β-Lactams via C-C Bond Activation.Journal of the American Chemical Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rui ZhangDepartment of Chemistry, The University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-9228-165X
Guangbin DongDepartment of Chemistry, The University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-1331-6015

Funding

Catalytic C-C Activation of Ketones - Renewal 01R01GM109054 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI DONG, GUANGBIN · 2013 to 2025
$3.9M
NIGMS NIH HHS R01 GM109054NIGMS NIH HHS R01GM109054
6 · The paper itself

Abstract

Skeletal rearrangements of amides provide rapid access to complex nitrogen-containing scaffolds from simple readily available starting materials. While classical reactions such as the Hofmann and Curtius rearrangements have been widely utilized in organic synthesis, recent advances in amide activation strategies have brought new types of transformations and offered many new applications. This review focuses on the development of amide skeletal rearrangement reactions over the past two decades. The content is organized based on the initial bond cleavage pathways: C─N bond cleavage, C─C bond cleavage, and C═O bond activation.

Indexed as

amidesC─C bond activationC─N bond activationfragmentationskeletal rearrangements

Identifiers

PMID40095718
PMCPMC12057600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.