Evidence map›Paper›PMID 40095512›Full record

ArticleJournal of clinical medicine2025

Comparison of Efficacy and Ocular Surface Assessment Between Preserved and Preservative-Free Brimonidine/Timolol Fixed-Combination Eye Drops in Glaucoma Patients: A Parallel-Grouped, Randomized Trial.

Myungjin Kim, Chang-Kyu Lee, Jonghoon Shin, Doah Kim, Seungsoo Rho

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Myungjin KimDepartment of Ophthalmology, CHA Bundang Medical Center, CHA University, Seongnam 13496, Republic of Korea.
Chang-Kyu LeeDepartment of Ophthalmology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Republic of Korea.ORCID 0000-0002-4023-232X
Jonghoon ShinDepartment of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.ORCID 0000-0003-1721-1253
Doah KimDepartment of Ophthalmology, CHA Bundang Medical Center, CHA University, Seongnam 13496, Republic of Korea.
Seungsoo RhoDepartment of Ophthalmology, CHA Bundang Medical Center, CHA University, Seongnam 13496, Republic of Korea.

Funding

Hanlim Pharm (South Korea) 0
6 · The paper itself

Abstract

The objectives of the study were to compare the efficacy and safety using ocular surface assessment between preserved and preservative-free brimonidine/timolol fixed-combination eye drops in glaucoma or ocular hypertension patients.

Indexed as

adherencebrimonidine/timololconjunctival staining scorecorneal staining scoredrug toleranceefficacyglaucomaocular hypertensionocular surface disease indexpreservative-freesafety

Identifiers

PMID40095512
PMCPMC11900319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.