Evidence map›Paper›PMID 40095355›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2025

Baicalein prevents skin damage, tumorigenesis and tumor growth in chronic ultraviolet B-irradiated hairless mice.

Yoshiyuki Kimura, Maho Sumiyoshi, Masahiko Taniguchi

Abstract read
PubMed Publisher
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yoshiyuki KimuraDepartment of Natural Product Sciences, Faculty of Pharmaceutical Sciences, Osaka Medical and Pharmaceutical University, Nasahara, Takatsuki City, Osaka, 569-1094, Japan. yoshiyukikimura6@gmail.com.ORCID http://orcid.org/0000-0003-3273-0393
Maho SumiyoshiDivision of Functional Histology, Department of Functional Biomedicine, Ehime University Graduate School of Medicine, Toon City, Ehime, 791-0295, Japan.
Masahiko TaniguchiDepartment of Natural Product Sciences, Faculty of Pharmaceutical Sciences, Osaka Medical and Pharmaceutical University, Nasahara, Takatsuki City, Osaka, 569-1094, Japan.

Funding

KAKENHI JP20K07804
6 · The paper itself

Abstract

Non-melanoma skin cancer accounted for over one million new cases, according to the Global Cancer Statistics 2020 report. Moreover, UV radiation causes photodamage (skin inflammation and angiogenesis), photoaging (increases in skin wrinkle and reduction in skin elasticity). This study investigated the preventive effects of baicalein against skin damage, aging, tumorigenesis and tumor growth in long-term UVB irradiated hairless mice. Five-week-old male mice were divided into the following groups: a non-UVB group (control), vehicle-treated UVB group (UVB control), and UVB groups treated with two different doses of baicalein (10 and 30 mg/kg, twice daily). The mice were exposed to UVB irradiation (36-192 mJ/cm

Indexed as

CarcinogenesisFlavanonesSkinSkin NeoplasmsUltraviolet RaysAnimalsCytokinesMaleMiceMice, HairlessSkin AgingVascular Endothelial Growth Factor AbaicaleinCytokinesFlavanonesVascular Endothelial Growth Factor ABaicaleinHIF-1αNF-κBSkin damageTumorigenesisUltraviolet B

Identifiers

PMID40095355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.