Evidence map›Paper›PMID 40095330›Full record

ArticleJapanese journal of ophthalmology2025

Impact of prolonged digital device use on acquired comitant esotropia: ACE-DD study 2.

Hirohito Iimori, Noriko Nishikawa, Sachiko Nishina, Tomoyo Yoshida, Takafumi Mori, Osamu Hieda, Akiko Hikoya, Miwa Komori, Shion Hayashi, Takashi Negishi and 11 more

Abstract readMulticenter Study
In one paragraph

Article in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Hirohito IimoriDepartment of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuka, 431-3192, Japan.
Noriko NishikawaDepartment of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan.
Sachiko NishinaDivision of Ophthalmology, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan.
Tomoyo YoshidaDivision of Ophthalmology, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan.
Takafumi MoriDepartment of Ophthalmology, Fukushima Medical University, Fukushima, Japan.
Osamu HiedaDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Akiko HikoyaDepartment of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuka, 431-3192, Japan.
Miwa KomoriDepartment of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuka, 431-3192, Japan.
Shion HayashiDivision of Ophthalmology, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan.
Takashi NegishiDepartment of Ophthalmology, Faculty of Medicine, Juntendo University, Bunkyo-ku, Tokyo, Japan.
Toshiaki GosekiDepartment of Ophthalmology, International University of Health and Welfare, Atami Hospital, Atami, Japan.
Yoshiko SugiyamaDepartment of Ophthalmology, Kanazawa University, Kanazawa, Japan.
Akiko KimuraDepartment of Ophthalmology, Hyogo Medical University, Nishinomiya, Japan.
Takeshi MorimotoDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan.
Yukiko ShimizuDepartment of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan.
Tamami ShimizuDepartment of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuka, 431-3192, Japan.
Yoshimi YokoyamaDepartment of Ophthalmology, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.
Hiroko SuzukiDepartment of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuka, 431-3192, Japan.
Sadao SuzukiDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Noriyuki AzumaDivision of Ophthalmology, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan.
Miho SatoDepartment of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuka, 431-3192, Japan. mihosato@hama-med.ac.jp.ORCID http://orcid.org/0000-0002-0389-6274

Funding

JSPS KAKENHI JP20K0978National Center for Child Health and Development 2021B-6National Center for Child Health and Development 30-2330-23
6 · The paper itself

Abstract

purposeTo investigate changes in strabismus angles in children and young adult patients with recent onset of constant acquired comitant esotropia (ACE) following instructions on hand-held digital devices (DD). STUDY

designProspective multicenter non-randomized interventional study.

methodsThis study included subjects aged 5-35 years who developed ACE within 1 year. Subjects were divided into two groups: (i) subjects who used DD for an average of ≥120 minutes/day for junior high-school students and older and ≥60 minutes/day for primary-school students and younger (DD+); and (ii) subjects who used DD for less than that (DD-) based on the questionnaire at the study's start. During the initial visit, glasses were prescribed when necessary; verbal instructions on DD use including time reduction and viewing-distance elongation were provided. For each group, strabismus angles at the initial visit and at 3 months were compared. Cure was defined as esophoria within 8 prism diopters without symptoms.

resultsIn total, 181 cases were investigated. At baseline, strabismus angles in DD+ and DD- groups were 23±14 PD and 25±15 PD at near and 25±13 PD and 27±14 PD at distance, respectively. At 3 months, they were 22±16 PD and 25±15 PD at near and 23±14 PD and 27±13 PD at distance, respectively. Only in the DD+ group, reduction in strabismus angle was observed, but this was not clinically significant. Ten and 1 subjects in DD+ and DD- groups were cured.

conclusionAlthough changes in strabismus angles were not large enough, DD use instructions were beneficial for some ACE subjects.

Indexed as

Computers, HandheldEsotropiaEye MovementsOculomotor MusclesVision, BinocularAdolescentAdultChildChild, PreschoolFemaleFollow-Up StudiesHumansMaleProspective StudiesSurveys and QuestionnairesTime FactorsAcquired esotropiaChildDigital deviceSmartphoneYoung adult

Identifiers

PMID40095330
PMCPMC12003580

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.