Trial reportClinical oral investigations2025
In-patient comparison of marginal bone loss after 4 months in immediately loaded, submucosal, and transmucosal dental implants using 3D scanning: a prospective clinical trial.
Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06408506 (In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months A Controlled Clinical Pilot Study), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months A Controlled Clinical Pilot Study
Who cites it
1 citing paper in PubMed.
- Influence of Immediate Versus Delayed Loading on Peri-Implant Bone Healing: A Comparative FEA Study of Titanium Threaded and Scaffold Dental Implants.Materials (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis prospective observational study aimed to evaluate the clinical outcomes and impact of different treatment protocols - immediate loading using a round gold bar retained overdenture on two implants, submucosal healing, and transmucosal healing - on circumferential marginal bone levels around dental implants. MATERIALS AND
methods20 patients requiring six implants in the edentulous lower jaw were included. Within each patient, 2 implants were assigned to submucosal healing, transmucosal healing, or immediate loading protocols. Marginal bone loss (MBL) was evaluated using 3D scanning at implant placement and after 4 months while raising a full-thickness flap. Periotest values (PTVs), the oral health impact profile (OHIP-14) and regular clinical evaluations were conducted for up to 2 years.
resultsThe submucosal group exhibited the least mean vertical MBL (-0.22 mm), significantly lower than the immediate (-0.39 mm) and transmucosal (-0.36 mm) groups (P = .001). Peri-implant bone surface area reduction was lowest in the submucosal group (-0.87 mm²) compared to the transmucosal (-4.58 mm²) and immediate (-6.66 mm²) protocols (P = .002). One submucosal healed implant and two immediately loaded implants were lost. Immediate loading provided high patient comfort and demonstrated successful outcomes both in terms of clinical data (PTVs, MBL) and patient-reported outcome measures (OHIP-14, VAS).
conclusionsSubmucosal and transmucosal healing protocols resulted in better marginal bone preservation compared to immediate loading. Although immediate loading enhanced patient comfort, it was associated with higher marginal bone loss. CLINICAL RELEVANCE: This study highlights the potential advantages of submucosal healing for marginal bone preservation and supports the use of three-dimensional scanning for precise bone loss evaluation, guiding clinical decision-making in implantology.
trial registrationClinicalTrials.gov Identifier: NCT06408506.
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