ArticlePsychopharmacology2025
Psychedelics and autobiographical memory - six open questions.
Article in Psychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Evaluating the evidence for repressed memory recovery in psychedelic contexts.Psychopharmacology · 2026Review
- Post-traumatic stress disorder symptoms following psychedelic use: a naturalistic survey study.Psychological medicine · 2026Article
- Molecules, meaning, and physiology: disentangling the active ingredients of psychedelic therapeutics.Frontiers in neuroscience · 2026Article
- Questioning the recovery of dissociated traumatic memories under psilocybin: comment on "Therapeutic emergence of dissociated traumatic memories during psilocybin treatment for anorexia nervosa".Journal of eating disorders · 2025Article
- Recalled childhood trauma and post-psychedelic trajectories of change in a mixed-methods study.Scientific reports · 2025Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleSince the earliest LSD research, psychedelics have been claimed to enhance autobiographical memory. Revisiting and processing autobiographical memories has further been suggested to be a major component of the therapeutic action of psychedelics. However, modern psychedelic research has largely neglected autobiographical elements of psychedelic experiences, and many vital questions remain unanswered.
objectivesWe present and discuss six open questions related to psychedelics and autobiographical memory: (1) Do psychedelics enhance autobiographical recall? (2) Is recall and processing of significant autobiographical (e.g., traumatic) memories a common part of psychedelic experiences? (3) Do psychedelics promote the development of false or inaccurate memories? (4) How do autobiographical memories change if they are recalled and reconsolidated under the effects of psychedelics? (5) What are memories of psychedelic experiences like? (6) Are autobiographical experiences under psychedelics of particular importance for their therapeutic effects?
resultsWe present the background and current limited state of evidence for each question and provide suggestions on how future studies could best address them.
conclusionsBesides advancing basic research, answering these pressing questions is highly relevant for the possible therapeutic use of psychedelics, both in terms of developing and optimizing new interventions and for avoiding iatrogenic harms. Ideally, future psychedelic-assisted interventions could harness the possible synergies between the effects of psychedelics and existing memory-based therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.