Evidence map›Paper›PMID 40094977›Full record

ReviewDie Anaesthesiologie2025

[Recommendations for time-limited trial in neurocritical care].

Angelika Alonso, Annette Rogge, Patrick Schramm, Urs Münch, Susanne Jöbges

Abstract readEnglish AbstractReview
In one paragraph

Review in Die Anaesthesiologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. [Neurological prognosis after cardiac arrest and resuscitation].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angelika AlonsoNeurologische Klinik, Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Deutschland.
Annette RoggeNordseeklinik Helgoland, Helgoland, Deutschland.
Patrick SchrammDIVI-Sektion Studien und Standards in der Neuromedizin, Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin (DIVI) e. V., Schumannstr. 2, 10117, Berlin, Deutschland.
Urs MünchDRK Kliniken Berlin, Berlin, Deutschland.
Susanne JöbgesKlinik für Anästhesiologie und Intensivmedizin (CVK/CCM), Charité - Universitätsmedizin Berlin Charité - Universitätsmedizin Berlin, corporate member der Freien Universität Berlin und der Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland. susanne.joebges@charite.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many acute brain disorders are associated with acute disorders of consciousness. In an emergency situation, life-saving measures are usually taken first and intensive care is initiated. If there is no significant improvement with recovery of consciousness in the first few days, very complex decision-making situations arise regularly. In neurointensive care, a time-limited therapy trial (TLT) is an important structuring element in treatment planning and communication, as a binding agreement between the treatment team and the patient or legal representative on a treatment concept for a defined period of time. Due to the prolonged neurological rehabilitation phase, the TLT in neurointensive care can also last weeks or months. This often requires interdepartmental communication (acute/rehabilitation/long-term care), re-evaluation and implementation in neurointensive care. The recommendations include the definition, empirical evidence and implementation suggestions for a TLT for critically ill neurointensive care patients.

Indexed as

Brain DiseasesCritical CareHumansFunctional statusNeurocritical carePrognosisQuality of lifeTime-limited trial

Identifiers

PMID40094977
PMCPMC11953182

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.