Evidence map›Paper›PMID 40094457›Full record

ArticleThe Journal of cell biology2025

Lipid juggling: Any1 scrambles membranes for endosome biogenesis.

Sinead Iduna Schwabl, Konstantin Adrian Siegmann, David Teis

Abstract read
In one paragraph

Article in The Journal of cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sinead Iduna SchwablInstitute of Molecular Biochemistry, Biocenter, Medical University of Innsbruck , Innsbruck, Austria.ORCID 0000-0003-2006-4696
Konstantin Adrian SiegmannInstitute of Molecular Biochemistry, Biocenter, Medical University of Innsbruck , Innsbruck, Austria.ORCID 0009-0008-6022-1936
David TeisInstitute of Molecular Biochemistry, Biocenter, Medical University of Innsbruck , Innsbruck, Austria.ORCID 0000-0002-8181-0253

Funding

Austrian Science Fund 10.55776/35874
6 · The paper itself

Abstract

Multivesicular bodies (MVBs) are crucial for membrane protein degradation and lipid homeostasis. A recent study by Gao and colleagues (https://doi.org/10.1083/jcb.202410013) identifies Any1 as a phospholipid scramblase that plays an important role in MVB biogenesis by coordinating membrane remodeling with lipid transfer through Vps13 at organelle contact sites.

Indexed as

EndosomesLipid MetabolismMultivesicular BodiesOrganelle BiogenesisPhospholipid Transfer ProteinsAnimalsHumansPhospholipid Transfer Proteins

Identifiers

PMID40094457
PMCPMC11912935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.