ArticleNano letters2025
Metal-Organic Frameworks-Based Microrockets for Controlled and Sustained Drug Release.
Article in Nano letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Microrobots for Precision Diagnosis and Treatment in the Digestive System: A Review of Actuation Mechanisms, Structural Design, Preclinical and Translational Applications.Micromachines · 2026Review
- Metal-Organic Frameworks in Food Biotechnology: Opportunities, Challenges, and Future Perspectives for Probiotic Delivery, Precision Fermentation, and Circular Food Systems.Nanomaterials (Basel, Switzerland) · 2026Review
- Acid-enhanced drinkable hydrogel co-delivering riboflavin-loaded nanozymes for orchestrated inflammation-immune modulation and redox homeostasis in colitis therapy.Journal of nanobiotechnology · 2026Article
- Integrative ensemble learning framework for forecasting controlled drug release based on Raman spectral signatures.Scientific reports · 2026Article
- Key Tumor Responsive ZIF-8 Nanocarriers for Effective Anti-Cancer Therapeutics.International journal of nanomedicine · 2026Review
- Biomedical Applications of Functionalized Composites Based on Metal-Organic Frameworks in Bone Diseases.Pharmaceutics · 2025Review
- Application of Nanodrug Delivery Systems in Enhancing Treatment of Gastritis and Gastric Cancer: A Systematic Evaluation of Targeted Therapy.Pharmaceutics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastritis, linked to chronic stress and poor diets, poses significant risks, including ulcers and gastric cancers. Current treatments involving frequent dosing of multiple drugs face challenges with patient nonadherence and antibiotic resistance. To overcome these issues, metal-organic framework (MOF)-based microrockets utilizing a zinc-powered engine were engineered with pH-sensitive coatings for targeted gastritis treatment. These microrockets can self-propel into the gastric mucus via bubble propulsion and slowly release pharmaceutical ingredients from MOF components. A poly(3,4-ethylenedioxythiophene) shell and pH-sensitive enteric coating is designed for protection of MOFs in acid while allowing sustained drug release at the mucosa's neutral pH. In vivo studies demonstrate these microrockets sustain a prolonged drug retention for 48 h. This biocompatible design represents a promising strategy for active and controlled drug delivery with sustained release in acidic environments, presenting the potential for diverse biomedical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.