Evidence map›Paper›PMID 40094277›Full record

ArticleTurkish archives of pediatrics2025

Pharmacoeconomic Analysis and Considerations for the Management of Kawasaki Disease in the Arab Countries-A Multinational, Multi-Institutional Project of the Kawasaki Disease Arab Initiative (Kawarabi) (A Project Methodology Paper).

Djouher Nait-Ladjemil, Ashraf S Harahsheh, Nadine Choueiter, Hala M Agha, Hanifa Alrabte, Sima Y Abu Al-Saoud, Hesham Al-Saloos, Khalfan Al Senaidi, Raed Alzyoud, Zainab Al Awadhi and 11 more

Abstract read
In one paragraph

Article in Turkish archives of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Djouher Nait-LadjemilCHU Sainte-Justine, University of Montreal, Montreal, Canada.
Ashraf S HarahshehGeorge Washington University School of Medicine and Health Sciences, Washington, USA.ORCID 0000-0002-2622-573X
Nadine ChoueiterMount Sinai Kravis Children's Hospital, Icahn School of Medicine, New York, USA.
Hala M AghaDivision of Pediatric Cardiology, Cairo University, Egypt.
Hanifa AlrabteDepartment of Pediatric Cardiology, Tripoli Children Hospital, Tripoli, Libya.
Sima Y Abu Al-SaoudDepartment of Pediatrics, Al-Quds University Faculty of Medicine, Makassed Hospital, Jerusalem, Palestine.
Hesham Al-SaloosDivision of Cardiology, Sidra Medicine, Clinical Pediatrics, Weill Cornell Medicine, Qatar.
Khalfan Al SenaidiDivision of Pediatric Cardiology, Sultan Qaboos University Hospital, Muscat, Oman.
Raed AlzyoudPediatric Immunology, Allergy, and Rheumatology Division, Queen Rania Children's Hospital, Amman, Jordan.
Zainab Al AwadhiAl Jalila Children's Speciality Hospital, Dubai, United Arab Emirates.
Reda BelbouabPediatric Department University Hospital, Mustapha Bacha Algiers, Algiers University Faculty of Medicine, Algiers, Algeria.
Asma BouazizHeadmaster of Children and Neonatal Department, Hôpital Régional Ben Arous, Tunisia.
Mona El GanzouryDivision of Pediatric Cardiology, Department of Pediatrics, Ain Shams UniversityFaculty of Medicine, Cairo, Egypt.
Zohra FitouriDivision of Rheumatology, Emergency Department of Béchir Hamza Pediatric Hospital of Tunis, Tunisia.
Alyaa KotbyPediatric Cardiology Division, Department of Pediatrics, Ain Shams University Faculty of Medicine, Cairo, Egypt.
Mohamed S LadjDepartment of Pediatrics, Djillali Belkhenchir University Hospital, Algiers University Faculty of Medicine, Algiers, Algeria.
Mohammed Mokhtar BekkarDepartment of Pediatrics, Pediatric Cardiology Unit, Oran University Faculty of Medicine, CHU Oran, Algeria.
Najat RugigeDepartment of Pediatric Cardiology, Benghazi Children Hospital, Benghazi University, Benghazi, Libya.
Aso Faeq SalihDepartment of Pediatric Cardiology, Children's Heart Hospital-Sulaimani College of Medicine-Sulaimani University, Al-Sulaimaniyah, Iraq.
Mohamed SulaimanKidsHeart Medical Center, Abu Dhabi, United Arab Emirates.
Nagib DahdahCHU Sainte-Justine, Montreal, Canada.ORCID 0000-0001-7715-3169

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Kawasaki disease (KD) poses a significant risk of childhood-acquired coronary artery disease. There is a notable scarcity of comprehensive KD data from low- and middleincome Arab countries, giving rise to concerns about the underestimation of KD outcomes. To bridge these gaps, the Kawasaki disease Arab initiative (Kawarabi) was established to reinforce education, advocacy, and enhance patients' health outcomes. This project's primary objective is to assess the economic burden and disease-related costs affecting KD management in the Arab world, contextualized within the economic status and healthcare infrastructure of each respective country. Materials and Methods: The project employs a thorough pharmacoeconomic (PE) analysis, emphasizing societal implications, including patient expenses, hospital costs, and impacts on both the public healthcare system and private insurers. A multifaceted cost analysis methodology considers the impact of delays in acute management and potential cardiac complications, addressing hypothetical scenarios to quantify costs associated with different outcomes. Results: Unique perspectives of PEs in Arab countries and its crucial role in informing healthcare decision-making are analyzed. The project delves into the transformative role of PEs in healthcare systems. The project's exploration of KD in the Arab world anticipates significant contributions to the global understanding of KD challenges. The commitment to overcoming obstacles and addressing health disparities through the transformative lens of PEs reflects a dedication to making a positive impact on KD-related public health. Conclusion: The project is emphasized by offering actionable recommendations for KD management in low- to moderate-income Arab countries, in particular, and the Middle East, in general.

Identifiers

PMID40094277
PMCPMC11963343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.