Evidence map›Paper›PMID 40094205›Full record

ArticleTurkish archives of pediatrics2025

Surfactant Therapy in Late Preterm Infants with Respiratory Distress in Türkiye: An Observational, Prospective, Multicenter Study.

Sumru Kavurt, Nihal Demirel, İstemi Han Çelik, Ahmet Yagmur Bas, Makbule Ercan, Beyza Özcan, Zehra Aslan, Demet Oğuz, Musa Turgut, Melike Kefeli Demirel and 9 more

Abstract read
In one paragraph

Article in Turkish archives of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sumru KavurtDepartment of Neonatology, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, University of Health Sciences, Ankara, Türkiye.ORCID 0000-0003-0329-1846
Nihal DemirelDepartment of Neonatology, Ankara Yıldırım Beyazıt University, Ankara, Türkiye.ORCID 0000-0003-2044-2212
İstemi Han ÇelikDepartment of Neonatology, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, University of Health Sciences, Ankara, Türkiye.ORCID 0000-0002-2952-8154
Ahmet Yagmur BasDepartment of Neonatology, Ankara Yıldırım Beyazıt University, Ankara, Türkiye.ORCID 0000-0002-1329-2167
Makbule ErcanDivision of Neonatology, Department of Pediatrics, Zonguldak Bülent Ecevit University Faculty of Medicine, Zonguldak, Türkiye.ORCID 0000-0003-2007-8676
Beyza ÖzcanDepartment of Neonatology, University of Health Sciences, Konya City Hospital, Konya, Türkiye.ORCID 0000-0002-8558-5540
Zehra AslanDepartment of Neonatology, Şanlıurfa Mehmet Akif İnan Training and Research Hospital, Şanlıurfa, Türkiye.ORCID 0000-0002-3469-7569
Demet OğuzDepartment of Neonatology, Başakşehir Çam ve Sakura City Hospital, İstanbul, Türkiye.ORCID 0000-0003-0727-4875
Musa TurgutDivision of Neonatology, Department of Pediatrics, Pamukkale University Faculty of Medicine, Denizli, Türkiye.ORCID 0000-0001-6474-0161
Melike Kefeli DemirelDepartment of Neonatology, Tepecik Training and Research Hospital, İzmir, Türkiye.ORCID 0000-0002-0043-2263
Nilay HakanDivision of Neonatology, Muğla Sıtkı Koçman University, Muğla, Türkiye.ORCID 0000-0002-6575-7640
Ali BülbülDepartment of Neonatology, Sarıyer Hamidiye Etfal Training and Research Hospital, İstanbul, Türkiye.ORCID 0000-0002-3510-3056
Kadir TekgündüzDivision of Neonatology, Department of Pediatrics, Atatürk University Faculty of Medicine, Erzurum, Türkiye.ORCID 0000-0001-6375-5644
Samet BenliDivision of Neonatology, Fırat University, Elazığ, Türkiye.ORCID 0000-0002-2006-0559
Hüseyin AltunhanDepartment of Neonatology, Necmettin Erbakan University Meram Medical Faculty, Konya, Türkiye.ORCID 0000-0003-0264-8671
Murat KonakDivision of Neonatology, Department of Pediatrics, Selçuk University Selçuklu Medical Faculty, Konya, Türkiye.ORCID 0000-0001-8728-4541
Ferda OzlüDivisions of Neonatology, Çukurova University Faculty of Medicine, Adana, Türkiye.ORCID 0000-0002-2092-8426
Oğuz TuncerDivision of Neonatology, Department of Pediatrics, Yüzüncü Yıl University Faculty of Medicine, Van, Türkiye.ORCID 0000-0003-3706-414X
Ozge AydemirDivision of Neonatology, Eskisehir Osmangazi University Faculty of Medicine, Eskişehir, Türkiye.ORCID 0000-0002-4106-0873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Surfactant therapy (ST) is commonly used in late preterm (LPT) infants with respiratory distress despite a lack of definitive recommendation for these infants. Our aim was to establish a national prospective database to evaluate the use of surfactants in LPT infants. Materials and Methods: A multicenter, prospective observational cohort study was conducted among LPT infants treated with surfactant between January 1, 2022, and December 31, 2022. Twenty neonatologists from 16 neonatal intensive care units (NICUs) participated in the study. Results: During the study period, a total of 3327 LPT infants were admitted to the participating NICUs. Among them, 1866 infants experienced respiratory distress, and 288 received surfactant treatment. In this study, respiratory distress syndrome (RDS) was the most common indication for surfactant administration, affecting 158 infants (54.8%), followed by congenital pneumonia in 79 infants (27.4%) and transient tachypnea of the newborn (TTN) in 32 infants (11.1%). Conclusion: We demonstrated that ST is administered with significant variability among LPT infants experiencing respiratory distress. Additionally, respiratory issues in LPT infants beyond RDS, such as congenital pneumonia and TTN, are also frequently treated with surfactant.

Identifiers

PMID40094205
PMCPMC11963293

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