Evidence map›Paper›PMID 40094151›Full record

ArticleTherapeutic advances in rare disease

Frequent report of vitamin deficiencies and use of supplements and complementary/alternative treatment approaches in patients with eosinophilic gastrointestinal diseases.

Brenderia A Cameron, Elizabeth T Jensen, Xiangfeng Dai, Chelsea Anderson, Ellyn Kodroff, Mary Jo Strobel, Amy Zicarelli, Sarah Gray, Amanda Cordell, Girish Hiremath and 1 more

Abstract read
In one paragraph

Article in Therapeutic advances in rare disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Segmental overlap is common in eosinophilic gastrointestinal diseases and impacts clinical presentation and treatment.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brenderia A CameronCenter for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Elizabeth T JensenDivision of Gastroenterology and Hepatology, Department of Medicine, Center for Gastrointestinal Biology and Disease, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Xiangfeng DaiDivision of Gastroenterology and Hepatology, Department of Medicine, Center for Gastrointestinal Biology and Disease,University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Chelsea AndersonDivision of Gastroenterology and Hepatology, Department of Medicine, Center for Gastrointestinal Biology and Disease,University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Ellyn KodroffCampaign Urging Research for Eosinophilic Disease (CURED), Lincolnshire, IL, USA.
Mary Jo StrobelAmerican Partnership for Eosinophilic Disorders (APFED), Atlanta, GA, USA.
Amy ZicarelliEosinophilic Family Coalition (EFC), Cincinnati, OH, USA.
Sarah GrayAusEE Inc, Pacific Paradise, QLD, Australia.ORCID https://orcid.org/0000-0002-3142-4151
Amanda CordellEOS Network, Colchester, Essex, UK.
Girish HiremathDivision of Pediatric Gastroenterology, Hepatology, and Nutrition, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, TN, USA.
Evan S DellonCenter for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, CB#7080, Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC 27599-7080, USA.ORCID https://orcid.org/0000-0003-1167-1101

Funding

PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Temitope O. Keku · 1985 to 2026
$30.5M
SHORT-TERM RESEARCH TRAININGT35DK007386 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Evan Samuel Dellon · 1986 to 2026
$4.1M
NIDDK NIH HHS P30 DK034987NIDDK NIH HHS T35 DK007386
6 · The paper itself

Abstract

Background: Eosinophilic gastrointestinal diseases (EGIDs) impact nutrition. Objectives: To assess the frequency of vitamin deficiencies, supplement use, and complementary/alternative-medication (CAM) use in EoE and non-EoE EGID patients. Design: Cross-sectional study. Methods: We surveyed members of EGID Partners (egidpartners.org), a patient-centered research network, to assess physician-diagnosed vitamin deficiencies, supplement use, and use of CAM in patients with EoE versus non-EoE EGIDs. Results: Of 81 EGID patients (58 EoE and 23 non-EoE EGID), self-reported frequency of vitamin deficiencies were higher in non-EoE EGIDs compared to EoE (61% vs 50%; Conclusion: Vitamin deficiencies and supplement/CAM use are frequent in EGIDs, highlighting the need for additional EGID treatment.

Indexed as

complementary and alternative medicationseosinophilic colitis vitamin deficiencyeosinophilic enteritiseosinophilic esophagitiseosinophilic gastritis

Identifiers

PMID40094151
PMCPMC11907540

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.